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Antibiotics in laboratory medicine [electronic resource] /
- Sixth edition.
- Philadelphia, PA : Lippincott Williams and Wilkins, a Wolters Kluwer business, 2015.
- 1 online resource : illustrations (some color)
Revised edition of: Antibiotics in laboratory medicine / [edited by] Victor Lorian. 5th ed. �2005.
Includes bibliographical references and index.
Perspectives : intersection of drug development, challenges of antimicrobial resistance, and predicting antimicrobial efficacy -- The breakpoint -- Antimicrobial susceptibility on solid media -- Susceptibility testing of antimicrobials in liquid media -- Antimicrobial susceptibility testing of anaerobic bacteria -- Antimycobacterial agents: in vitro susceptibility testing and mechanisms of action and resistance. -- Antifungal drugs: mechanisms of action, drug resistance, susceptibility testing, and assays of activity in biologic fluids -- Antimicrobial susceptibility testing for some atypical microorganisms (Chlamydia, Mycoplasma, Rickettsia, Ehrlichia, Coxiella, and Spirochetes) -- Applications, significance of, and methods for the measurement of antimicrobial concentrations in human body fluids -- Molecular methods for detection of antibacterial resistance genes: rationale and applications. -- Molecular mechanisms of action for antimicrobial agents: general principles and mechanisms for selected classes of antibiotics -- Antiviral agents for HIV, hepatitis, cytomegalovirus, and influenza: susceptibility testing methods, modes of action, and resistance -- Disinfectants and antiseptics: modes of action, mechanisms of resistance, and testing regimens -- Evaluation of antimicrobials in experimental animal infections -- Extravascular antimicrobial distribution and the respective blood and urine concentrations in humans -- Appendix: antiinfective resistance resource guide.
"Antibiotics in Laboratory Medicine has been the defining reference source on evaluating the effectiveness of antibiotic compounds in treating infectious diseases for over 35 years. This thoroughly updated 6th Edition, edited by Daniel Amsterdam and featuring contributions from an elite team of leading international experts, equips you with all the latest methods for analyzing the mechanisms of activity/resistance of various pathogens, assessing their susceptibility to potential treatments, and detecting drug resistance and multi-drug resistance"--Publisher's description.
9781496324399 1496324390 9781469883632 1469883635
Microbial sensitivity tests. Antibiotics--Analysis. Drug resistance in microorganisms. Antibiotics--Analysis. Drug resistance in microorganisms. Microbial sensitivity tests. Microbial Sensitivity Tests. Anti-Bacterial Agents--pharmacology. Drug Resistance, Microbial--physiology.