MARC details
000 -LEADER |
fixed length control field |
03992nam a22004815i 4500 |
001 - CONTROL NUMBER |
control field |
978-981-19-7122-8 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
DE-He213 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20240729133705.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
221208s2022 si | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
ISBN |
9789811971228 |
-- |
978-981-19-7122-8 |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
MFG |
Source |
bicssc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
MED075000 |
Source |
bisacsh |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
MFG |
Source |
thema |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal author |
Gao, Yuansheng. |
Relator term |
author. |
Relator code |
aut |
-- |
http://id.loc.gov/vocabulary/relators/aut |
245 10 - TITLE STATEMENT |
Title |
Biology of Vascular Smooth Muscle |
Subtitle |
: Vasoconstriction and Dilatation / |
250 ## - EDITION |
Edition statement |
2nd ed. 2022. |
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
Place of production, publication, distribution, manufacture |
Singapore : |
Name of producer, publisher, distributor, manufacturer |
Springer Nature Singapore : |
-- |
Imprint: Springer, |
Date of production, publication, distribution, manufacture, or copyright notice |
2022. |
300 ## - PHYSICAL DESCRIPTION |
Physical description |
XV, 424 p. 1 illus. |
Other physical details |
online resource. |
336 ## - CONTENT TYPE |
Content type term |
text |
Content type code |
txt |
Source |
rdacontent |
337 ## - MEDIA TYPE |
Media type term |
computer |
Media type code |
c |
Source |
rdamedia |
338 ## - CARRIER TYPE |
Carrier type term |
online resource |
Carrier type code |
cr |
Source |
rdacarrier |
505 0# - CONTENTS |
Contents |
Architecture of the vessel wall -- Ultrastructure of vascular smooth muscle -- Vascular endothelium -- Electrical and mechanical properties of vascular smooth muscle -- Biochemistry of the contractile proteins of smooth muscle -- Metabolism of vascular smooth muscle -- Neurotransmitters -- Endothelium-derived factors -- Local metabolic factors -- Shear stress, myogenic response, and blood flow autoregulation -- Intracellular Ca2+ regulation -- Regulation of myosin light chain phosphorylation -- Cyclic AMP signaling -- Cyclic GMP signaling -- MicroRNAs and vasoreactivity -- Extracellular vesicles as unique signaling messengers -- Genetic and epigenetic modification -- Coronary vasoreactivity -- Cerebral vasoreactivity -- Pulmonary vasoreactivity -- Renal vasoreactivity -- Hypoxic vasoreactivity -- Ageing and vasoreactivity. |
520 ## - ABSTRACT |
Abstract |
This book provides a concise yet comprehensive review of the morphological, biochemical, electrical, mechanical, and metabolic properties of vascular smooth muscle, the regulation of vascular activities and the intracellular signaling involved. It particularly focuses on newly identified vasoactive agents, enzymes and transduction mechanisms. It also discusses the latest findings in the regulation of cerebral, coronary and pulmonary circulation as well as vascular activity under hypoxia and ageing. The second edition intends to update the contents of the first edition with the latest achievements in the regulation of vascular activities from biochemical, structural, genetic, physiological, and pharmacological aspects. In addition, two new chapters related to microRNA and extracellular vesicles have been added to reflect their newly discovered important roles in vascular activities. The contraction and dilatation activities of vasculature are of fundamental importance for maintaining circulation homeostasis and adapting to physiological changes. Over the last four decades, there have been significant advances in our understanding of the biochemical, structural, genetic, physiological, and pharmacological aspects of vascular activity regulation, and these insights into the responsiveness of blood vessels under normal and pathophysiological conditions help to provide valuable weapons in the fight vascular diseases. The book is of interest to researchers and graduate students, both in basic research and in clinic settings, in the field of vascular biology. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Human physiology. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Physiology. |
9 (RLIN) |
7429 |
650 #0 - SUBJECT HEADINGS |
Subject term |
Internal medicine. |
9 (RLIN) |
6654 |
650 #0 - SUBJECT HEADINGS |
Subject term |
Medicine |
General subdivision |
Research. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Biology |
General subdivision |
Research. |
650 14 - SUBJECT HEADINGS |
Subject term |
Human Physiology. |
650 24 - SUBJECT HEADINGS |
Subject term |
Physiology. |
9 (RLIN) |
7429 |
650 24 - SUBJECT HEADINGS |
Subject term |
Internal Medicine. |
9 (RLIN) |
6654 |
650 24 - SUBJECT HEADINGS |
Subject term |
Biomedical Research. |
710 2# - ADDED CORPORATE NAME |
Added corporate author |
SpringerLink (Online service) |
856 ## - ONLINE RESOURCE |
Uniform Resource Identifier |
<a href="#gotoholdings">#gotoholdings</a> |
Link text |
Access resource |
245 ## - TITLE STATEMENT |
Medium |
[E-Book] |
347 ## - DIGITAL FILE CHARACTERISTICS |
File type |
text file |
Encoding format |
PDF |
Source |
rda |
912 ## - |
-- |
ZDB-2-SBL |
912 ## - |
-- |
ZDB-2-SXB |