MARC details
000 -LEADER |
fixed length control field |
03857nam a22004455i 4500 |
001 - CONTROL NUMBER |
control field |
978-981-16-7589-8 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
DE-He213 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20240729133944.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
220329s2022 si | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
ISBN |
9789811675898 |
-- |
978-981-16-7589-8 |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PSC |
Source |
bicssc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
SCI072000 |
Source |
bisacsh |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PSC |
Source |
thema |
245 10 - TITLE STATEMENT |
Title |
Stem Cell Production |
Subtitle |
: Processes, Practices and Regulations / |
250 ## - EDITION |
Edition statement |
1st ed. 2022. |
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
Place of production, publication, distribution, manufacture |
Singapore : |
Name of producer, publisher, distributor, manufacturer |
Springer Nature Singapore : |
-- |
Imprint: Springer, |
Date of production, publication, distribution, manufacture, or copyright notice |
2022. |
300 ## - PHYSICAL DESCRIPTION |
Physical description |
XI, 272 p. 1 illus. |
Other physical details |
online resource. |
336 ## - CONTENT TYPE |
Content type term |
text |
Content type code |
txt |
Source |
rdacontent |
337 ## - MEDIA TYPE |
Media type term |
computer |
Media type code |
c |
Source |
rdamedia |
338 ## - CARRIER TYPE |
Carrier type term |
online resource |
Carrier type code |
cr |
Source |
rdacarrier |
505 0# - CONTENTS |
Contents |
Chapter 1. Stem Cell Therapy: Significance and Applications of Stem Cell Products in the Tissue Engineering and Regenerative Medicine -- Chapter 2. GLP Requirements of Stem Cells -- Chapter 3. Current Good Manufacturing Practice (CGMP) Facility and Production of Stem Cell -- Chapter 4. Global Regulatory Frameworks and Quality Standards for Stem Cells Therapy and Regenerative Medicines -- Chapter 5. Stem Cell Bioreactors: Design, Structure and Operation of Stem Cell Bioreactors -- Chapter 6. Stem Cell Culture and Expansion: Role of culture, Types of Cells, Growth Conditions, Media Nutrients, Growth Factors, Growth Phase Cycle -- Chapter 7. UP Scaling of Clinical Grade Stem Cell Production-Upstream Processing (USP) and Downstream Processing (DSP) Operations of Cell Expansion, Harvesting, Detachment, Separation, Washing and Concentration Steps, and the Regulatory Requirements -- Chapter 8. Characterization of Clinical-GradeStem Cells: Microscopic, Cellular, Molecular, and Functional Characterization of Stem Cells and their Products According to Regulatory Requirements for FDA Approval -- Chapter 9. Stem Cell Safety and Sterility Testing: A Promising Approach in Regenerative Medicine -- Chapter 10. Stem Cells Storage, Packaging and Transportation -- Chapter 11. Stem Cell Clinical Trials and Stem Cell Market.-. |
520 ## - ABSTRACT |
Abstract |
This book examines the technologies and processes for the development and commercial production of stem cells according to cGMP guidelines. The initial chapter of the book discusses the therapeutic potentials of stem cells for the treatment of various diseases, including degenerative disorders and genetic diseases. The book then reviews the recent developments in the cultivation of stem cells in bioreactors, including critical cultural parameters, possible bioreactor configuration and integrations of novel technologies in bioprocess developmental stages. The book also introduces microscopic, molecular, and cellular techniques for characterization of stem cells for regulatory approvals. Further, it describes optimal cell transporting conditions to maintain cell viability and properties. Further, it summarizes characterization strategies of clinical grade stem cells for stem cell therapy. This book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Stem cells. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Regenerative medicine. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Therapeutics. |
650 14 - SUBJECT HEADINGS |
Subject term |
Stem Cell Biology. |
650 24 - SUBJECT HEADINGS |
Subject term |
Regenerative Medicine and Tissue Engineering. |
650 24 - SUBJECT HEADINGS |
Subject term |
Therapeutics. |
700 1# - ADDED PERSONAL NAME |
Added personal author |
Khan, Firdos Alam. |
Relator term |
editor. |
710 2# - ADDED CORPORATE NAME |
Added corporate author |
SpringerLink (Online service) |
856 ## - ONLINE RESOURCE |
Uniform Resource Identifier |
<a href="#gotoholdings">#gotoholdings</a> |
Link text |
Access resource |
245 ## - TITLE STATEMENT |
Medium |
[E-Book] |
347 ## - DIGITAL FILE CHARACTERISTICS |
File type |
text file |
Encoding format |
PDF |
Source |
rda |
912 ## - |
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ZDB-2-SBL |
912 ## - |
-- |
ZDB-2-SXB |