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Sphingolipid Metabolism and Metabolic Disease (Record no. 101116)

MARC details
000 -LEADER
fixed length control field 03680nam a22004815i 4500
001 - CONTROL NUMBER
control field 978-981-19-0394-6
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240729134113.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 220503s2022 si | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9789811903946
-- 978-981-19-0394-6
072 #7 - SUBJECT CATEGORY CODE
Subject category code MBGR
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED106000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code MBGR
Source thema
245 10 - TITLE STATEMENT
Title Sphingolipid Metabolism and Metabolic Disease
250 ## - EDITION
Edition statement 1st ed. 2022.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Singapore :
Name of producer, publisher, distributor, manufacturer Springer Nature Singapore :
-- Imprint: Springer,
Date of production, publication, distribution, manufacture, or copyright notice 2022.
300 ## - PHYSICAL DESCRIPTION
Physical description VIII, 213 p. 1 illus.
Other physical details online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
490 1# - SERIES TITLE
Series statement Advances in Experimental Medicine and Biology,
International Standard Serial Number 2214-8019 ;
Volume 1372
505 0# - CONTENTS
Contents Chapter 1: Sphingolipids and Cholesterol -- Chapter 2: Sphingolipids in adipose: kin or foe? -- Chapter 3: De novo sphingolipid biosynthesis in atherosclerosis -- Chapter 4: Serine Palmitoyltransferase Subunit 3 and Metabolic Diseases -- Chapter 5: Molecular mechanisms of sphingolipid transport on plasma lipoproteins -- Chapter 6: Sphingosine 1-phosphate metabolism and signaling -- Chapter 7: Sphingomyelin synthase family and phospholipase Cs -- Chapter 8: Sphingolipid metabolism and signaling in endothelial cell functions -- Chapter 9: Cholesterol metabolism in chronic kidney disease: physiology, pathologic mechanisms, and treatment -- Chapter 10: Sphingolipids and asthma -- Chaper 11: Manifold Roles of Ceramide Metabolism in Nonalcoholic Fatty Liver Disease and Liver Cancer -- Chapter 12: Drug development in the field of sphinogolipid metabolism -- Chapter 13: Rare diseases in glycosphingolipid metabolism.
520 ## - ABSTRACT
Abstract This book provides an up-to-date review of the fundamentals of sphingolipid metabolism and its role in metabolic diseases. Focusing on the sphingolipid de novo synthesis pathway, the effect of sphingomyelin, ceramide, and sphingosine-1-phosphate, and linkage between sphingolipids and other lipids, such as cholesterol, it covers serine palmitoyltransferase, ceramide synthases, ceramidases, sphingosine kinases, and sphingomyelin synthases, and more. While highlighting how rare diseases related to abnormal glycosphingolipid metabolism, this publication introduces sphingolipid metabolism-related diseases, such as lung diseases and cancers, as well as sphingolipid circadian regulation. The book demonstrates advances and limitations of research on sphingolipid metabolism and its roles in metabolic diseases and other diseases. It offers graduate students and researchers a coherent overview of sphingolipids, as well as the limitations of current research in the field, and promotes further studies on metabolic diseases, as well as pharmaceutical research on drug discovery based on sphingolipid de novo synthase.
650 #0 - SUBJECT HEADINGS
Subject term Medicine
General subdivision Research.
650 #0 - SUBJECT HEADINGS
Subject term Biology
General subdivision Research.
650 #0 - SUBJECT HEADINGS
Subject term Diseases.
650 #0 - SUBJECT HEADINGS
Subject term Internal medicine.
9 (RLIN) 6654
650 14 - SUBJECT HEADINGS
Subject term Biomedical Research.
650 24 - SUBJECT HEADINGS
Subject term Diseases.
650 24 - SUBJECT HEADINGS
Subject term Internal Medicine.
9 (RLIN) 6654
700 1# - ADDED PERSONAL NAME
Added personal author Jiang, Xian-Cheng.
Relator term editor.
710 2# - ADDED CORPORATE NAME
Added corporate author SpringerLink (Online service)
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Advances in Experimental Medicine and Biology,
International Standard Serial Number 2214-8019 ;
Volume number/sequential designation 1372
856 ## - ONLINE RESOURCE
Uniform Resource Identifier <a href="#gotoholdings">#gotoholdings</a>
Link text Access resource
245 ## - TITLE STATEMENT
Medium [E-Book]
347 ## - DIGITAL FILE CHARACTERISTICS
File type text file
Encoding format PDF
Source rda
912 ## -
-- ZDB-2-SBL
912 ## -
-- ZDB-2-SXB
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Source of acquisition Total Checkouts Date last seen Uniform Resource Identifier Price effective from Koha item type
        Hillingdon Hospitals Library Services (Hillingdon Hospitals NHS Foundation) Hillingdon Hospitals Library Services (Hillingdon Hospitals NHS Foundation) Online 02/05/2024 Springer BiomedLifeSc   02/05/2024 https://go.openathens.net/redirector/nhs?url=https://doi.org/10.1007/978-981-19-0394-6 02/05/2024 Electronic book
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