MARC details
| 000 -LEADER |
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| fixed length control field |
05220nam a22005175i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-3-030-84744-9 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20240821193454.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
211201s2022 sz | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| ISBN |
9783030847449 |
| -- |
978-3-030-84744-9 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MNS |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MED065000 |
| Source |
bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MNS |
| Source |
thema |
| 245 10 - TITLE STATEMENT |
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| Title |
Orthobiologics |
| Subtitle |
: Injectable Therapies for the Musculoskeletal System / |
| 250 ## - EDITION |
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| Edition statement |
1st ed. 2022. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
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| Place of production, publication, distribution, manufacture |
Cham : |
| Name of producer, publisher, distributor, manufacturer |
Springer International Publishing : |
| -- |
Imprint: Springer, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2022. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Physical description |
XI, 402 p. 73 illus., 66 illus. in color. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 505 0# - CONTENTS |
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| Contents |
I. Injectable OrthoBiologics: Formulations and Rationale 1. Bone marrow-derived cultured stromal cells and Bone Marrow Concentrate -- 2. Adipose-derived cultured stromal cells and Stromal Vascular Fraction from adipose tissue -- 3. Synovial-derived cultured stromal cells -- 4. Amniotic, Placenta, and Umbilical cord-derived cultured stromal cells -- 5. Allogeneic cells: pros and cons -- 6. Steroid hormones -- 7. Cytokines, chemokines, alpha-2-macroglobulin, growth factors -- 8. Platelet-rich plasma: leucocyte-rich, leukocyte-poor, autologous conditioned serum, autologous protein solution -- 9. Amniotic tissue extract, placenta tissue extract -- 10. Extracellular vesicles (exosomes) -- II. Injectable OrthoBiolologics: evaluation methods and results based on pathology and anatomy -- 11. Rotator cuff tendinopathy: cell therapy -- 12. Rotator cuff tendinopathy: biologics -- 13. Tennis elbow: cell therapy -- 14. Tennis elbow: cell therapy biologics -- 15. Patellar tendinopathy: cell therapy -- 16. Patellar tendinopathy: biologics -- 17. Achilles tendinopathy: cell therapy -- 18. Achilles tendinopathy: biologics -- 19. Plantar Fasciitis: cell therapy -- 20. Plantar Fasciitis: biologics -- 21. Ligament lesions: cell therapy -- 22. Ligament lesions: biologics -- 23. Meniscal lesions: cell therapy -- 24. Meniscal lesions: biologics -- 25. Muscle lesions: cell therapy -- 26. Muscle lesions: biologics -- 27. Fractures (incl. Nonunions): cell therapy -- 28. Fractures (incl. Nonunions): biologics -- 29. Cartilage lesions and Osteoarthritis of the knee: cell therapy -- 30. Cartilage lesions and Osteoarthritis of the knee: biologics -- 31. Cartilage lesions and Osteoarthritis of the hip and ankle: cell therapy -- 32. Cartilage lesions and Osteoarthritis of the hip and ankle: biologics -- III. Future directions 33. Pluripotent stem cells: Embryonic/Fetal stem cells and induced pluripotent stem (iPS) cells -- 34. Gene therapy -- 35.Stimulation of the intrinsic stromal cell niche -- 36 Conclusions. |
| 520 ## - ABSTRACT |
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| Abstract |
This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies - ranging from tendinopathies through non-unions to articular degenerative processes - as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts. |
| 650 #0 - SUBJECT HEADINGS |
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| Subject term |
Orthopedics. |
| 650 #0 - SUBJECT HEADINGS |
|---|
| Subject term |
Sports medicine. |
| 650 #0 - SUBJECT HEADINGS |
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| Subject term |
Regenerative medicine. |
| 650 #0 - SUBJECT HEADINGS |
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| Subject term |
Medical sciences. |
| 650 14 - SUBJECT HEADINGS |
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| Subject term |
Orthopaedics. |
| 650 24 - SUBJECT HEADINGS |
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| Subject term |
Sports Medicine. |
| 650 24 - SUBJECT HEADINGS |
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| Subject term |
Regenerative Medicine and Tissue Engineering. |
| 650 24 - SUBJECT HEADINGS |
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| Subject term |
Health Sciences. |
| 700 1# - ADDED PERSONAL NAME |
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| Added personal author |
Filardo, Giuseppe. |
| Relator term |
editor. |
| 700 1# - ADDED PERSONAL NAME |
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| Added personal author |
Mandelbaum, Bert R. |
| Relator term |
editor. |
| 700 1# - ADDED PERSONAL NAME |
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| Added personal author |
Muschler, George F. |
| Relator term |
editor. |
| 700 1# - ADDED PERSONAL NAME |
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| Added personal author |
Rodeo, Scott A. |
| Relator term |
editor. |
| 700 1# - ADDED PERSONAL NAME |
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| Added personal author |
Nakamura, Norimasa. |
| Relator term |
editor. |
| 710 2# - ADDED CORPORATE NAME |
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| Added corporate author |
SpringerLink (Online service) |
| 856 ## - ONLINE RESOURCE |
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| Uniform Resource Identifier |
<a href="#gotoholdings">#gotoholdings</a> |
| Link text |
Access resource |
| 245 ## - TITLE STATEMENT |
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| Medium |
[E-Book] |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
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| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 912 ## - |
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ZDB-2-SME |
| 912 ## - |
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ZDB-2-SXM |