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Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers (Record no. 101789)

MARC details
000 -LEADER
fixed length control field 04009nam a22004095i 4500
001 - CONTROL NUMBER
control field 978-3-030-80546-3
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240729134623.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 220103s2022 sz | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9783030805463
-- 978-3-030-80546-3
072 #7 - SUBJECT CATEGORY CODE
Subject category code MJ
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED045000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code MJ
Source thema
245 10 - TITLE STATEMENT
Title Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers
Subtitle : Multidisciplinary Management /
250 ## - EDITION
Edition statement 1st ed. 2022.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Cham :
Name of producer, publisher, distributor, manufacturer Springer International Publishing :
-- Imprint: Springer,
Date of production, publication, distribution, manufacture, or copyright notice 2022.
300 ## - PHYSICAL DESCRIPTION
Physical description XVIII, 315 p. 29 illus., 26 illus. in color.
Other physical details online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
505 0# - CONTENTS
Contents Introduction -- State-of-the art and ongoing developments -- Clinical cases debate: neoadjuvant checkpoint inhibition vs standard chemotherapy -- Slideshow of tumor samples before and after checkpoint inhibition -- Ongoing trials and clinical trials endpoints debate: the role of pathological response as a surrogate of survival endpoints -- State-of-the-art and future role of molecular biomarkers for patient selection -- Background of immunotherapy trials in prostate cancer -- Clinical case debate: immunotherapy vs alternative therapies in the neoadjuvant and adjuvant setting of localized, high-risk prostate cancer -- Cytoreductive nephrectomy in the era of targeted therapy and immunotherapy -- Clinical cases debate: Neoadjuvant vs adjuvant immunotherapy in localized RCC -- Benchmark of surgical safety results -- What the scientific data tell us about predictive biomarkers of immunotherapy efficacy across the GU malignancies -- Clinical cases debate: biomarker-driven patient selection vs unselective perioperative strategies. .
520 ## - ABSTRACT
Abstract This book aims to provide readers with a current overview of enrolling trials with immune-checkpoint inhibitors in the preoperative setting of localized bladder cancer, renal cell carcinoma, and prostate cancer. The advent of immunotherapy has revolutionized treatments of genitourinary malignancy and evolved strategies for multidisciplinary management. This book explains neoadjuvant checkpoint inhibitors in localized genitourinary cancers, providing insights into the mechanisms of response and development of resistance of cancer cells to immunotherapy. It debates optimal trial design of preoperative checkpoint inhibitors in GU tumors, including optimal endpoints and the role of pathologic response as a surrogate endpoint of survival. It also illuminates clinical management of patients with organ-confined GU tumors, such as side effect management and perioperative safety, before providing an overview of biomarker use for patient selection across the early-stage GU malignancies. Lastly, the book provides the reader with the most up-to-date data emerging from clinical trials involving immunotherapy in early-stage GU malignancies. Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers: Multidisciplinary Management provides a comprehensive review of the field, serving as a valuable resource for urologists, medical oncologists, pathologists, fellows in urologic oncology, upper-level residents training in urology and medical oncology, as well as pharmacists interested in RCC clinicians.
650 #0 - SUBJECT HEADINGS
Subject term Internal medicine.
9 (RLIN) 6654
650 14 - SUBJECT HEADINGS
Subject term Internal Medicine.
9 (RLIN) 6654
700 1# - ADDED PERSONAL NAME
Added personal author Necchi, Andrea.
Relator term editor.
700 1# - ADDED PERSONAL NAME
Added personal author Spiess, Philippe E.
Relator term editor.
710 2# - ADDED CORPORATE NAME
Added corporate author SpringerLink (Online service)
856 ## - ONLINE RESOURCE
Uniform Resource Identifier <a href="#gotoholdings">#gotoholdings</a>
Link text Access resource
245 ## - TITLE STATEMENT
Medium [E-Book]
347 ## - DIGITAL FILE CHARACTERISTICS
File type text file
Encoding format PDF
Source rda
912 ## -
-- ZDB-2-SME
912 ## -
-- ZDB-2-SXM
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Source of acquisition Total Checkouts Date last seen Uniform Resource Identifier Price effective from Koha item type
        Hillingdon Hospitals Library Services (Hillingdon Hospitals NHS Foundation) Hillingdon Hospitals Library Services (Hillingdon Hospitals NHS Foundation) Online 02/05/2024 Springer BiomedLifeSc   02/05/2024 https://go.openathens.net/redirector/nhs?url=https://doi.org/10.1007/978-3-030-80546-3 02/05/2024 Electronic book
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