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Endolysosomal Voltage-Dependent Cation Channels (Record no. 103288)

MARC details
000 -LEADER
fixed length control field 03413nam a22005055i 4500
001 - CONTROL NUMBER
control field 978-3-031-31523-7
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240729135823.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 230426s2023 sz | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9783031315237
-- 978-3-031-31523-7
072 #7 - SUBJECT CATEGORY CODE
Subject category code MMG
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED071000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code MKG
Source thema
245 10 - TITLE STATEMENT
Title Endolysosomal Voltage-Dependent Cation Channels
250 ## - EDITION
Edition statement 1st ed. 2023.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Cham :
Name of producer, publisher, distributor, manufacturer Springer International Publishing :
-- Imprint: Springer,
Date of production, publication, distribution, manufacture, or copyright notice 2023.
300 ## - PHYSICAL DESCRIPTION
Physical description X, 304 p. 1 illus.
Other physical details online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
490 1# - SERIES TITLE
Series statement Handbook of Experimental Pharmacology,
International Standard Serial Number 1865-0325 ;
Volume 278
505 0# - CONTENTS
Contents Part I: Physiological Functions of Endo-lysosomal Cation Channels -- NAADP-Mediated Ca2+ Signalling -- NAADP-Dependent TPC Current -- NAADP-Evoked Ca2+ Signaling: The DUOX2-HN1L/JPT2-Ryanodine Receptor 1 Axis -- TPC Functions in the Immune System -- Lysosomal Ion Channels and Lysosome- 1 Organelle Interactions -- TRPML1 and TFEB, an Intimate Affair -- Lysosomal Potassium Channels -- Part II Structure and Composition of TPC and TRPML Channels -- Structure and Function of Plant and Mammalian TPC Channels -- A Structural Overview of TRPML1 and the TRPML Family -- Endo-Lysosomal Two-Pore Channels and Their Protein Partners -- Part III: Tools and Methods to Characterize Endolysosomal Cation Channels -- Electrophysiological Techniques on the Study of Endolysosomal Ion Channels -- The Plant Vacuole as Heterologous System to Characterize the Functional Properties of TPC Channels -- Expanding the Toolbox: Novel Modulators of Endolysosomal Cation Channels -- Characterization of Endo-Lysosomal Cation Channels Using Calcium Imaging.
520 ## - ABSTRACT
Abstract This book covers the molecular structures and the cellular and in vivo function of endosomes and lysosomes, i.e. intracellular vesicles which are involved in many cellular processes such as endocytosis, intracellular trafficking, degradation of material from inside (e.g. autophagy) and outside the cell as well as exocytosis. Membranes of endolysosomal organelles contain an amazing number and diversity of ion channels. These ion channels are the topic of the present book that focusses on describing the structure, the biophysical properties, physiological functions of endolysosomal ion channels at the molecular, cellular and in vivo level. .
650 #0 - SUBJECT HEADINGS
Subject term Pharmacology.
9 (RLIN) 7400
650 #0 - SUBJECT HEADINGS
Subject term Physiology.
9 (RLIN) 7429
650 #0 - SUBJECT HEADINGS
Subject term Cytology.
650 #0 - SUBJECT HEADINGS
Subject term Life sciences.
650 14 - SUBJECT HEADINGS
Subject term Pharmacology.
9 (RLIN) 7400
650 24 - SUBJECT HEADINGS
Subject term Physiology.
9 (RLIN) 7429
650 24 - SUBJECT HEADINGS
Subject term Cell Biology.
650 24 - SUBJECT HEADINGS
Subject term Life Sciences.
700 1# - ADDED PERSONAL NAME
Added personal author Wahl-Schott, Christian.
Relator term editor.
700 1# - ADDED PERSONAL NAME
Added personal author Biel, Martin.
Relator term editor.
710 2# - ADDED CORPORATE NAME
Added corporate author SpringerLink (Online service)
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Handbook of Experimental Pharmacology,
International Standard Serial Number 1865-0325 ;
Volume number/sequential designation 278
856 ## - ONLINE RESOURCE
Uniform Resource Identifier <a href="#gotoholdings">#gotoholdings</a>
Link text Access resource
245 ## - TITLE STATEMENT
Medium [E-Book]
347 ## - DIGITAL FILE CHARACTERISTICS
File type text file
Encoding format PDF
Source rda
912 ## -
-- ZDB-2-SBL
912 ## -
-- ZDB-2-SXB
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Source of acquisition Total Checkouts Date last seen Uniform Resource Identifier Price effective from Koha item type
        Hillingdon Hospitals Library Services (Hillingdon Hospitals NHS Foundation) Hillingdon Hospitals Library Services (Hillingdon Hospitals NHS Foundation) Online 02/05/2024 Springer BiomedLifeSc_2023   02/05/2024 https://go.openathens.net/redirector/nhs?url=https://doi.org/10.1007/978-3-031-31523-7 02/05/2024 Electronic book
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