MARC details
000 -LEADER |
fixed length control field |
04179nam a22005535i 4500 |
001 - CONTROL NUMBER |
control field |
978-3-031-14740-1 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
DE-He213 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20240729135850.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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221215s2023 sz | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
ISBN |
9783031147401 |
-- |
978-3-031-14740-1 |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PSF |
Source |
bicssc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
SCI017000 |
Source |
bisacsh |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PSF |
Source |
thema |
245 14 - TITLE STATEMENT |
Title |
The Networking of Chaperones by Co-Chaperones |
250 ## - EDITION |
Edition statement |
3rd ed. 2023. |
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
Place of production, publication, distribution, manufacture |
Cham : |
Name of producer, publisher, distributor, manufacturer |
Springer International Publishing : |
-- |
Imprint: Springer, |
Date of production, publication, distribution, manufacture, or copyright notice |
2023. |
300 ## - PHYSICAL DESCRIPTION |
Physical description |
XV, 429 p. 53 illus., 46 illus. in color. |
Other physical details |
online resource. |
336 ## - CONTENT TYPE |
Content type term |
text |
Content type code |
txt |
Source |
rdacontent |
337 ## - MEDIA TYPE |
Media type term |
computer |
Media type code |
c |
Source |
rdamedia |
338 ## - CARRIER TYPE |
Carrier type term |
online resource |
Carrier type code |
cr |
Source |
rdacarrier |
490 1# - SERIES TITLE |
Series statement |
Subcellular Biochemistry, |
International Standard Serial Number |
2542-8810 ; |
Volume |
101 |
505 0# - CONTENTS |
Contents |
Chapter 1: GrpE, Hsp110/Grp170, HspBP1/Sil1 and BAG domain proteins: Nucleotide exchange factors for Hsp70 molecular chaperones -- Chapter 2: Functions of the Hsp90-Binding FKBP Immunophilins -- Chapter 3: Hsp70/Hsp90 organising protein (Hop): coordinating much more than chaperones -- Chapter 4: Specification of Hsp70 function by Hsp40 Co-Chaperones -- Chapter 5: Cdc37 as a Co-chaperone to Hsp90 -- Chapter 6: p23 and Aha1 - Distinct functions promote client maturation -- Chapter 7: Beyond chaperoning: UCS proteins emerge as regulators of myosin-mediated cellular processes -- Chapter 8: Chaperonin - Co-Chaperonin Interactions -- Chapter 9: Co-chaperones of the human endoplasmic reticulum: an update -- Chapter 10: J Domain Proteins Orchestrate the Multifunctionality of Hsp70s in Mitochondria: Insights from Mechanistic and Evolutionary Analyses -- Chapter 11: Impact of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity -- Chapter 12: CHIP: a co-chaperone for degradation by the proteasome and lysosome -- Chapter 13: HSP70-HSP90 chaperone networking in protein misfolding disease. |
520 ## - ABSTRACT |
Abstract |
Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is the dynamic integration of the processes of protein folding, degradation and translocation to ensure that cellular function is finely tuned in space and time. This third edition of the book The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by co-chaperones, a diverse cohort of non-client proteins. Since the second edition was released, not only has knowledge deepened on how co-chaperones act as nodes to network and functionalise chaperones, but an understanding of their broader biological function has started to emerge. The third edition provides new and updated chapters highlighting recent developments and emerging themes on co-chaperones, such as their extracellular functions, their role in human disease and their status as putative drug targets. The book is a useful resourcefor both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology. . |
650 #0 - SUBJECT HEADINGS |
Subject term |
Protein folding. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Proteins . |
9 (RLIN) |
7571 |
650 #0 - SUBJECT HEADINGS |
Subject term |
Post-translational modification. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Cytology. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Biomolecules. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Physical biochemistry. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Macromolecules. |
650 14 - SUBJECT HEADINGS |
Subject term |
Protein Folding. |
650 24 - SUBJECT HEADINGS |
Subject term |
Protein Biochemistry. |
650 24 - SUBJECT HEADINGS |
Subject term |
Post-translational Modifications. |
650 24 - SUBJECT HEADINGS |
Subject term |
Cell Biology. |
650 24 - SUBJECT HEADINGS |
Subject term |
Structural Biology. |
700 1# - ADDED PERSONAL NAME |
Added personal author |
Edkins, Adrienne L. |
Relator term |
editor. |
700 1# - ADDED PERSONAL NAME |
Added personal author |
Blatch, Gregory L. |
Relator term |
editor. |
710 2# - ADDED CORPORATE NAME |
Added corporate author |
SpringerLink (Online service) |
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
Uniform title |
Subcellular Biochemistry, |
International Standard Serial Number |
2542-8810 ; |
Volume number/sequential designation |
101 |
856 ## - ONLINE RESOURCE |
Uniform Resource Identifier |
<a href="#gotoholdings">#gotoholdings</a> |
Link text |
Access resource |
245 ## - TITLE STATEMENT |
Medium |
[E-Book] |
347 ## - DIGITAL FILE CHARACTERISTICS |
File type |
text file |
Encoding format |
PDF |
Source |
rda |
912 ## - |
-- |
ZDB-2-SBL |
912 ## - |
-- |
ZDB-2-SXB |