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Senescence Back and Forth (Record no. 103548)

MARC details
000 -LEADER
fixed length control field 03557nam a22005175i 4500
001 - CONTROL NUMBER
control field 978-3-031-32276-1
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240729140049.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 230610s2023 sz | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9783031322761
-- 978-3-031-32276-1
072 #7 - SUBJECT CATEGORY CODE
Subject category code PSA
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI072000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code PSA
Source thema
100 1# - MAIN ENTRY--PERSONAL NAME
Personal author Nydegger, Urs.
Relator term author.
Relator code aut
-- http://id.loc.gov/vocabulary/relators/aut
245 10 - TITLE STATEMENT
Title Senescence Back and Forth
250 ## - EDITION
Edition statement 1st ed. 2023.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Cham :
Name of producer, publisher, distributor, manufacturer Springer International Publishing :
-- Imprint: Springer,
Date of production, publication, distribution, manufacture, or copyright notice 2023.
300 ## - PHYSICAL DESCRIPTION
Physical description XXIII, 132 p. 38 illus., 30 illus. in color.
Other physical details online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
505 0# - CONTENTS
Contents Senescence opposed to longevity -- Genetics, the language of Proteomics -- Plants Uncover Senescence Animals Way Off Humans -- Rejuvenation stops Senescence -- Overlap of Senescence with Disease -- Mosaic Restricted to the Individuum -- Remaining Time until Death -- Laboratory Checkups -- eroprotectors.
520 ## - ABSTRACT
Abstract This book is about lifelong ageing of humans. The basic biochemical and genetic mechanisms remain ill known, and differ among individuals. The book starts out to explore the plant and animal kingdoms to answer questions human ageing needs for understanding. First, we come to scrutinize time running out and what 'normal' means with impacts on the genome and on protein half- lives and function. Ageing goes beyond biochemical skid treated by geroprotector drugs, including biosimilars; albeit early diagnosis with standard medical laboratory assays, here addressed, sheds light with focus on basic research. Modern tools, including machine learning, and DNA technology, e.g. genomics, have already provided for unanticipated insights. The chapters then turn around senescence of the entire organism based on variable ageing of single organs embedded in neuronal networks . Psychological stress factors, dementia opposed to vigilance, and distinction of ageing from overt disease arecontrasting in humans and are opposed in the book. Senescence, seen as a one way track may be reverted into rejuvenation, made possible by insights into immunosenescence and genomic approaches. Risk management in health insurance finds important clues in this book. The topics addressed between the book covers help to understand the trend to the ever- prolonging life expectancy beyond the centenarian age group; nursing care takers and pharmaceutical industry are invited to understand what' is going on in senior people to make their geriatric population remain fit or become frail.
650 #0 - SUBJECT HEADINGS
Subject term Aging.
9 (RLIN) 12870
650 #0 - SUBJECT HEADINGS
Subject term Medicine
General subdivision Research.
650 #0 - SUBJECT HEADINGS
Subject term Biology
General subdivision Research.
650 #0 - SUBJECT HEADINGS
Subject term Public health.
650 #0 - SUBJECT HEADINGS
Subject term Biotechnology.
9 (RLIN) 5393
650 #0 - SUBJECT HEADINGS
Subject term Psychiatry.
650 14 - SUBJECT HEADINGS
Subject term Ageing.
9 (RLIN) 5161
650 24 - SUBJECT HEADINGS
Subject term Biomedical Research.
650 24 - SUBJECT HEADINGS
Subject term Public Health.
650 24 - SUBJECT HEADINGS
Subject term Chemical Bioengineering.
650 24 - SUBJECT HEADINGS
Subject term Psychiatry.
700 1# - ADDED PERSONAL NAME
Added personal author Lung, Thomas.
Relator term author.
710 2# - ADDED CORPORATE NAME
Added corporate author SpringerLink (Online service)
856 ## - ONLINE RESOURCE
Uniform Resource Identifier <a href="#gotoholdings">#gotoholdings</a>
Link text Access resource
245 ## - TITLE STATEMENT
Medium [E-Book]
347 ## - DIGITAL FILE CHARACTERISTICS
File type text file
Encoding format PDF
Source rda
912 ## -
-- ZDB-2-SBL
912 ## -
-- ZDB-2-SXB
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Source of acquisition Total Checkouts Date last seen Uniform Resource Identifier Price effective from Koha item type
        Hillingdon Hospitals Library Services (Hillingdon Hospitals NHS Foundation) Hillingdon Hospitals Library Services (Hillingdon Hospitals NHS Foundation) Online 02/05/2024 Springer BiomedLifeSc_2023   02/05/2024 https://go.openathens.net/redirector/nhs?url=https://doi.org/10.1007/978-3-031-32276-1 02/05/2024 Electronic book
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