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Neurotoxicity of Aluminum (Record no. 103597)

MARC details
000 -LEADER
fixed length control field 03839nam a22004215i 4500
001 - CONTROL NUMBER
control field 978-981-99-1592-7
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240729140118.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 230708s2023 si | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9789819915927
-- 978-981-99-1592-7
072 #7 - SUBJECT CATEGORY CODE
Subject category code PSAN
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI089000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code PSAN
Source thema
245 10 - TITLE STATEMENT
Title Neurotoxicity of Aluminum
250 ## - EDITION
Edition statement 2nd ed. 2023.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Singapore :
Name of producer, publisher, distributor, manufacturer Springer Nature Singapore :
-- Imprint: Springer,
Date of production, publication, distribution, manufacture, or copyright notice 2023.
300 ## - PHYSICAL DESCRIPTION
Physical description XVIII, 313 p. 1 illus.
Other physical details online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
505 0# - CONTENTS
Contents Chapter 1 Overview of the relationship between aluminum exposure and health of human being.-Chapter 2 The Chemistry of Human Exposure to Aluminum -- Chapter 3 Entry and Deposit of Aluminum in Brain -- Chapter 4 Aluminum as a CNS and immune system toxin across the life span.-Chapter 5 Occupational exposure to aluminum and cognitive impairment -- Chapter 6 Debated relationship between Exposure to Aluminum in Daily Life and Alzheimer's Disease -- Chapter 7 Animal Model of Aluminum-Induced Alzheimer's like Disease -- Chapter 8 Aluminum-induced AD-like Pathological Features.-Chapter 9 Aluminum induced neural cells death -- Chapter 10 Aluminum-Induced Electrophysiological Variation, Synaptic Plasticity Impairment, and Related Mechanism.-Chapter 11 Cross Talk Between Aluminum and Genetic Susceptibility -- Chapter 12 Epigenetic modification in aluminum-induced neuron death and synaptic impairment -- Chapter 13 Neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD) -- Chapter 14 Alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects.
520 ## - ABSTRACT
Abstract This book reviews the scientific literature and the authors' own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer's disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, its relation to neurofibrillary tangles and amyloid beta-the pathological features of AD, and the possible mechanism of aluminum inducing these pathological features. Further, the book stresses the importance of aluminum's complex speciation chemistry in relation to biology, and details aluminum's mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal's debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed, and more recently the relationship between aluminum-induced epigenetic modification on DNA and non-coding RNAs and neuron death and synaptic impairment. The second edition updates eight chapters according to the most recent researches. Content about aluminum-induced AD-like pathological features, neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD) and alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects is also added. In closing, this book provides readers with a systematic summary of aluminum neurotoxicity.
650 #0 - SUBJECT HEADINGS
Subject term Neurosciences.
650 #0 - SUBJECT HEADINGS
Subject term Pharmacology.
9 (RLIN) 7400
650 14 - SUBJECT HEADINGS
Subject term Neuroscience.
650 24 - SUBJECT HEADINGS
Subject term Pharmacology.
9 (RLIN) 7400
700 1# - ADDED PERSONAL NAME
Added personal author Niu, Qiao.
Relator term editor.
710 2# - ADDED CORPORATE NAME
Added corporate author SpringerLink (Online service)
856 ## - ONLINE RESOURCE
Uniform Resource Identifier <a href="#gotoholdings">#gotoholdings</a>
Link text Access resource
245 ## - TITLE STATEMENT
Medium [E-Book]
347 ## - DIGITAL FILE CHARACTERISTICS
File type text file
Encoding format PDF
Source rda
912 ## -
-- ZDB-2-SBL
912 ## -
-- ZDB-2-SXB
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Source of acquisition Total Checkouts Date last seen Uniform Resource Identifier Price effective from Koha item type
        Hillingdon Hospitals Library Services (Hillingdon Hospitals NHS Foundation) Hillingdon Hospitals Library Services (Hillingdon Hospitals NHS Foundation) Online 02/05/2024 Springer BiomedLifeSc_2023   02/05/2024 https://go.openathens.net/redirector/nhs?url=https://doi.org/10.1007/978-981-99-1592-7 02/05/2024 Electronic book
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