The Topological Model of Genome and Evolution (Record no. 103700)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03442nam a22004575i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-981-99-4318-0 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240821195035.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230919s2023 si | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| ISBN | 9789819943180 |
| -- | 978-981-99-4318-0 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSAK |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | SCI029000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSAK |
| Source | thema |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal author | Chhaya, Pradeep. |
| Relator term | author. |
| Relator code | aut |
| -- | http://id.loc.gov/vocabulary/relators/aut |
| 245 14 - TITLE STATEMENT | |
| Title | The Topological Model of Genome and Evolution |
| Subtitle | : Understanding the Origin and Nature of Life / |
| 250 ## - EDITION | |
| Edition statement | 1st ed. 2023. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Singapore : |
| Name of producer, publisher, distributor, manufacturer | Springer Nature Singapore : |
| -- | Imprint: Springer, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2023. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Physical description | XXIII, 546 p. 1 illus. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 505 0# - CONTENTS | |
| Contents | Chapter 1_Nature of Life: Structuralism and functionalities -- Chapter 2_Nature of Relationship Between: A Genotype and A Phenotype -- Chapter 3_Nature of Genomic Architecture: A Topological Model of Genome -- Chapter 4_Biological Algorithm of Involution: Ontology of Gene Expressions -- Chapter 5_Nature of Developmental Processes in Mammals -- Chapter 6_Nature of Aging Process: Genomic Ontology of Aging -- Chapter 7_Nature of Genomic Evolution: Its imprint in Cancer -- Chapter 8_Nature of Regulatory Genome: The Evolution and Natural Selection of Genotope -- Chapter 9_Principles of Genomic Evolution. |
| 520 ## - ABSTRACT | |
| Abstract | This book deals with the missing link in the domain of functional genomics viz. genomic architecture. It begins with a deconstruction of the Darwinian paradigm using the proposed model of modified involuted manifolds. It recasts the process of natural selection as a process of information transfer. Using a topological model, this book outlines a new genomic architecture. The key argument for this proposed model is that some such structuralism has always been implicit in genomics. The proposed model fits very well with the known genomic characteristics and allows to separate the regulatory genome from the transcriptive genomes. The model is capable of discerning modular architecture of genomes with different genomic functionalities existing in hierarchical relationships and demonstrates that genomes act as units of selection and as the environment for the individual genes which act as competing species. Towards the end, the book also examines the role of genomic evolution in cancer and the principles of natural selection and evolution of the genotype. The regulatory genome is also discussed, with an emphasis on its evolution and natural selection. It is a valuable source for researchers working in functional genomics, mathematical modeling in biology and evolutionary genomics. . |
| 650 #0 - SUBJECT HEADINGS | |
| Subject term | Genetics. |
| 650 #0 - SUBJECT HEADINGS | |
| Subject term | Evolution (Biology). |
| 650 #0 - SUBJECT HEADINGS | |
| Subject term | Evolutionary genetics. |
| 650 14 - SUBJECT HEADINGS | |
| Subject term | Genetics and Genomics. |
| 650 24 - SUBJECT HEADINGS | |
| Subject term | Evolutionary Biology. |
| 650 24 - SUBJECT HEADINGS | |
| Subject term | Evolutionary Theory. |
| 650 24 - SUBJECT HEADINGS | |
| Subject term | Evolutionary Genetics. |
| 710 2# - ADDED CORPORATE NAME | |
| Added corporate author | SpringerLink (Online service) |
| 856 ## - ONLINE RESOURCE | |
| Uniform Resource Identifier | <a href="#gotoholdings">#gotoholdings</a> |
| Link text | Access resource |
| 245 ## - TITLE STATEMENT | |
| Medium | [E-Book] |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 912 ## - | |
| -- | ZDB-2-SBL |
| 912 ## - | |
| -- | ZDB-2-SXB |
| Withdrawn status | Lost status | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Source of acquisition | Total Checkouts | Date last seen | Uniform Resource Identifier | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hillingdon Hospitals Library Services (Hillingdon Hospitals NHS Foundation) | Hillingdon Hospitals Library Services (Hillingdon Hospitals NHS Foundation) | Online | 02/05/2024 | Springer BiomedLifeSc_2023 | 02/05/2024 | https://go.openathens.net/redirector/nhs?url=https://doi.org/10.1007/978-981-99-4318-0 | 02/05/2024 | Electronic book |