MARC details
000 -LEADER |
fixed length control field |
04710nam a22004815i 4500 |
001 - CONTROL NUMBER |
control field |
978-3-031-12390-0 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
DE-He213 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20240821195043.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
221018s2023 sz | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
ISBN |
9783031123900 |
-- |
978-3-031-12390-0 |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PSAN |
Source |
bicssc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
SCI089000 |
Source |
bisacsh |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PSAN |
Source |
thema |
245 10 - TITLE STATEMENT |
Title |
Glycobiology of the Nervous System |
250 ## - EDITION |
Edition statement |
2nd ed. 2023. |
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
Place of production, publication, distribution, manufacture |
Cham : |
Name of producer, publisher, distributor, manufacturer |
Springer International Publishing : |
-- |
Imprint: Springer, |
Date of production, publication, distribution, manufacture, or copyright notice |
2023. |
300 ## - PHYSICAL DESCRIPTION |
Physical description |
XII, 501 p. 96 illus., 73 illus. in color. |
Other physical details |
online resource. |
336 ## - CONTENT TYPE |
Content type term |
text |
Content type code |
txt |
Source |
rdacontent |
337 ## - MEDIA TYPE |
Media type term |
computer |
Media type code |
c |
Source |
rdamedia |
338 ## - CARRIER TYPE |
Carrier type term |
online resource |
Carrier type code |
cr |
Source |
rdacarrier |
490 1# - SERIES TITLE |
Series statement |
Advances in Neurobiology, |
International Standard Serial Number |
2190-5223 ; |
Volume |
29 |
505 0# - CONTENTS |
Contents |
1. Introduction to the complexity of cell surface and tissue matrix glycoconjugates. -- 2. Introduction to cells comprising the nervous system. -- 3. Synthesis -- processing -- and function of N-glycans in N-glycoproteins. -- 4. Synthesis of O-linked glycoconjugates in the nervous system. -- 5. Chemistry and function of glycosaminoglycans in the nervous system. -- 6. Use of glycan-targeted antibodies/lectins to study the expression/function of glycosyltransferases in the nervous system. -- 7. Capillary electrophoresis and mass spectrometry-based glycosylation analysis in glycomics and glycoproteomics. -- 8. Structural analysis of oligosaccharides and glycoconjugates using NMR. -- 9. Glycolipid and glycoprotein expression during neural development. -- 10. Gangliosides and cell surface ganglioside glycohydrolases in the nervous system (request them to include gal-cer and sulfatide). -- 11. Role of myelin-associated glycoproteins in the peripheral nervous system. -- 12. Glycosignaling: a general review. -- 13. Glycosphingolipids in the regulation of the nervous system. -- 14. O-GlcNAcylation of neuronal proteins: Roles in neuronal functions and in neurodegeneration. -- 15. Glycoconjugates in nuclear membranes. -- 16. N-glycosylation in regulation of the nervous system. -- 17. Role of carbohydrates in the interaction of pathogens with neural cells. -- 18. Glycoconjugate changes in aging and age-related diseases. -- 19. Gangliosides and glycolipids in neurodegenerative disorders. -- 20. Inborn errors of glycosphingolipid catabolism and potential treatment. -- 21. Neurological aspects of human glycosylation disorders. -- 22. Glycoconjugates and neural tumors. -- 23. Galectins and neuroinflammation . -- 24. Glycoconjugates and neuroimmunological diseases. -- 25. Targeting nanoparticle drug carriers to the brain. -- 26. Use of quantum dots to treat inherited lysosomal storage diseases. -- 27. MALDI-FTICR MS imaging of nervous system glycoconjugates. |
520 ## - ABSTRACT |
Abstract |
This new edition provides comprehensive coverage of the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic fundamental principles as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. New topics include a detailed discussion of cells found within the nervous system, an extensive listing of congenital disorders of glycosylation of both proteins and lipids, the roles of glycans in neuronal axon growth/guidance and voltage-gated channels, the role of intra-lysosomal luminal vesicles in lysosomal storage disorders, and, in the time of the COVID-19 pandemic, the role of carbohydrates in infection by SARS-CoV-2. The breadth and depth of topics covered make this an essential reference for those new to the field as well as for more experienced investigators. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Neurosciences. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Zoology. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Neurochemistry. |
9 (RLIN) |
7117 |
650 14 - SUBJECT HEADINGS |
Subject term |
Neuroscience. |
650 24 - SUBJECT HEADINGS |
Subject term |
Zoology. |
650 24 - SUBJECT HEADINGS |
Subject term |
Neurochemistry. |
9 (RLIN) |
7117 |
700 1# - ADDED PERSONAL NAME |
Added personal author |
Schengrund, Cara-Lynne. |
Relator term |
editor. |
700 1# - ADDED PERSONAL NAME |
Added personal author |
Yu, Robert K. |
Relator term |
editor. |
710 2# - ADDED CORPORATE NAME |
Added corporate author |
SpringerLink (Online service) |
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
Uniform title |
Advances in Neurobiology, |
International Standard Serial Number |
2190-5223 ; |
Volume number/sequential designation |
29 |
856 ## - ONLINE RESOURCE |
Uniform Resource Identifier |
<a href="#gotoholdings">#gotoholdings</a> |
Link text |
Access resource |
245 ## - TITLE STATEMENT |
Medium |
[E-Book] |
347 ## - DIGITAL FILE CHARACTERISTICS |
File type |
text file |
Encoding format |
PDF |
Source |
rda |
912 ## - |
-- |
ZDB-2-SBL |
912 ## - |
-- |
ZDB-2-SXB |