MARC details
000 -LEADER |
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04364nam a22005535i 4500 |
001 - CONTROL NUMBER |
control field |
978-3-031-36390-0 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
DE-He213 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20240729140319.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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231103s2023 sz | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
ISBN |
9783031363900 |
-- |
978-3-031-36390-0 |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PSD |
Source |
bicssc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PSBC |
Source |
bicssc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
SCI008000 |
Source |
bisacsh |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PSD |
Source |
thema |
245 10 - TITLE STATEMENT |
Title |
RNA Structure and Function |
250 ## - EDITION |
Edition statement |
1st ed. 2023. |
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
Place of production, publication, distribution, manufacture |
Cham : |
Name of producer, publisher, distributor, manufacturer |
Springer International Publishing : |
-- |
Imprint: Springer, |
Date of production, publication, distribution, manufacture, or copyright notice |
2023. |
300 ## - PHYSICAL DESCRIPTION |
Physical description |
XI, 666 p. 134 illus., 123 illus. in color. |
Other physical details |
online resource. |
336 ## - CONTENT TYPE |
Content type term |
text |
Content type code |
txt |
Source |
rdacontent |
337 ## - MEDIA TYPE |
Media type term |
computer |
Media type code |
c |
Source |
rdamedia |
338 ## - CARRIER TYPE |
Carrier type term |
online resource |
Carrier type code |
cr |
Source |
rdacarrier |
490 1# - SERIES TITLE |
Series statement |
RNA Technologies, |
International Standard Serial Number |
2197-9758 ; |
Volume |
14 |
505 0# - CONTENTS |
Contents |
1. Computational Tools for Functional Analysis of Circular RNAs -- 2. The Hidden Layer of RNA Variants -- 3. Functional Role of Non-Coding RNAs in Prostate Cancer: From Biomarker to Therapeutic Targets -- 4. The structure, function, and modification of non-coding RNAs in cardiovascular system,- 5. Contribution of RNA Species in Sexually Transmitted Infections -- 6. Hypoxia and Epithelial-to-Mesenchymal Transition (EMT) in Cancer: A Non-Coding RNA Perspective -- 6. A Study on the Role of piRNAs in Cancer Epigenetics -- 7. Modified Nucleosides as RNA Components. Structure, Biological Role and Drug Design -- 8. Multifaceted Functions of RNA m6A Modification in Modulating Regulated Cell Death -- 9. Incorporation of Pseudouridine into RNA for Biochemical and Biophysical Studies -- 10. Molecular Dynamics Simulations of Chemically Modified Ribonucleotides. |
520 ## - ABSTRACT |
Abstract |
This book focuses on the current status of our understanding of RNA, a key biological molecule. The various RNAs covered are messenger RNA, ribosomal RNA, transfer RNA, noncoding RNAs, modified nucleosides, and RNA enzymes. The different chapters detail methods to investigate RNA structure and function, the chemistry of modified RNAs, and the latest advances in our understanding of the vast array of biological processes in which RNA is involved. RNA, in one form or another, touches almost everything in a cell. RNA has both structural and catalytic properties. RNA fulfills a broad range of functions. These molecules are no longer seen as passive elements transferring the genetic information from DNA into proteins but regulate the activity of genes during development, cellular differentiation, and changing environments. RNAs are involved in various aspects of cell physiology and disease development. Discoveries of RNA with unexpected diverse functions in healthy and diseased cells,such as the role of RNA as both the source and countermeasure to cancer or severe viral infection, stimulate new trends, passion, and solutions for molecular medicine. In this book, fundamental questions about the biochemical and genetic importance of RNA, how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, how to determine RNA structure and how to apply RNA in treatment of diseases. This book is an essential resource for researches in academia and industry contributing to the development of new RNA therapeutics. The book is geared toward scientists from the graduate level on up and particularly appeals to active investigators in RNA biology, molecular biology, and biochemistry. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Biomolecules. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Physical biochemistry. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Macromolecules. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Biochemistry. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Medical genetics. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Cytology. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Genetics. |
650 14 - SUBJECT HEADINGS |
Subject term |
Structural Biology. |
650 24 - SUBJECT HEADINGS |
Subject term |
Biochemistry. |
650 24 - SUBJECT HEADINGS |
Subject term |
Medical Genetics. |
650 24 - SUBJECT HEADINGS |
Subject term |
Cell Biology. |
650 24 - SUBJECT HEADINGS |
Subject term |
Genetics and Genomics. |
700 1# - ADDED PERSONAL NAME |
Added personal author |
Barciszewski, Jan. |
Relator term |
editor. |
710 2# - ADDED CORPORATE NAME |
Added corporate author |
SpringerLink (Online service) |
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
Uniform title |
RNA Technologies, |
International Standard Serial Number |
2197-9758 ; |
Volume number/sequential designation |
14 |
856 ## - ONLINE RESOURCE |
Uniform Resource Identifier |
<a href="#gotoholdings">#gotoholdings</a> |
Link text |
Access resource |
245 ## - TITLE STATEMENT |
Medium |
[E-Book] |
347 ## - DIGITAL FILE CHARACTERISTICS |
File type |
text file |
Encoding format |
PDF |
Source |
rda |
912 ## - |
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ZDB-2-SBL |
912 ## - |
-- |
ZDB-2-SXB |