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Neuromodulative treatment with percutaneous tibial nerve stimulation for intractable detrusor instability:outcomes following a shortened 6-week protocol. (Record no. 75800)

MARC details
000 -LEADER
fixed length control field 04972cam a2200229 4500
001 - CONTROL NUMBER
control field NMDX6643
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 120401t2010 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 14644096
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Yoong, W.
240 ## - UNIFORM TITLE
Uniform title <a href="BJU international.">BJU international.</a>
245 ## - TITLE STATEMENT
Title Neuromodulative treatment with percutaneous tibial nerve stimulation for intractable detrusor instability:outcomes following a shortened 6-week protocol.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Date of publication, distribution, etc. 2010
500 ## - GENERAL NOTE
General note NMUH Staff Publications
500 ## - GENERAL NOTE
General note Available in print at Ferriman Library
500 ## - GENERAL NOTE
General note 106
520 ## - SUMMARY, ETC.
Summary, etc. &lt;p style="margin: 0px 0px 0.5em; line-height: 17.999801635742188px;"&gt;&lt;span style="font-size: 8pt;"&gt;&lt;strong&gt;OBJECTIVE:&lt;/strong&gt; To describe our initial outcome data&amp;nbsp;&lt;span class="highlight"&gt;following&lt;/span&gt;&amp;nbsp;a&amp;nbsp;&lt;span class="highlight"&gt;shortened&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;6-week&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;treatment&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;protocol&lt;/span&gt;&amp;nbsp;with&amp;nbsp;&lt;span class="highlight"&gt;percutaneous&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;tibial&lt;/span&gt;&lt;span class="highlight"&gt;nerve&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;stimulation&lt;/span&gt;&amp;nbsp;(PTNS) in women with overactive bladder syndrome (OABS) unresponsive to bladder retraining and anticholinergic therapy.&lt;/span&gt;&lt;/p&gt;&lt;h4 style="margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left; line-height: 17.999801635742188px;"&gt;&lt;span style="font-size: 8pt;"&gt;PATIENTS AND METHODS:&lt;/span&gt;&lt;/h4&gt;&lt;p style="margin: 0px 0px 0.5em; line-height: 17.999801635742188px;"&gt;&lt;span style="font-size: 8pt;"&gt;This was a prospective observational study over a 6-month period. In all, 43 women with OABS refractory to medical therapy were treated with a&amp;nbsp;&lt;span class="highlight"&gt;shortened&lt;/span&gt;&amp;nbsp;PTNS&amp;nbsp;&lt;span class="highlight"&gt;protocol&lt;/span&gt;&amp;nbsp;that consisted of 6 weekly 30 min sessions. Bladder symptom diaries and health-related quality of life (HRQL) assessed using the short-form seven-item self-report. Incontinence Impact Questionnaire (IIQ-7) were completed before and after&amp;nbsp;&lt;span class="highlight"&gt;treatment&lt;/span&gt;. A positive response was defined as: (i) OAB symptoms no longer being bothersome; (ii) reduction by half in frequency episodes and (iii) reduction by 25% in IIQ-7&lt;span class="highlight"&gt;outcomes&lt;/span&gt;.&lt;/span&gt;&lt;/p&gt;&lt;h4 style="margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left; line-height: 17.999801635742188px;"&gt;&lt;span style="font-size: 8pt;"&gt;RESULTS:&lt;/span&gt;&lt;/h4&gt;&lt;p style="margin: 0px 0px 0.5em; line-height: 17.999801635742188px;"&gt;&lt;span style="font-size: 8pt;"&gt;All 43 women (median age 55.3 years) completed six treatments with a positive response rate of 69.7%. In the positive responders, the median daytime and nocturnal frequency was reduced by half after 6 weeks of&amp;nbsp;&lt;span class="highlight"&gt;treatment&lt;/span&gt;&amp;nbsp;(11.8 vs 6.9 and 3.5 vs 1.8, respectively, P &amp;lt; 0.05) and the patients reported fewer urge leak episodes per 24 h (median 3.5 vs 2.4, P &amp;lt; 0.05). The median IIQ-7 scores improved by 25% (30.4 vs 24.3, P &amp;lt; 0.05) in responders, while the median number of pads changed in 24 h also decreased by 34% (3.8 vs 2.5, P &amp;lt; 0.05). The median acceptability of the technique when scored by Visual Analogue Score was 9.6/10 and no side-effects were reported.&lt;/span&gt;&lt;/p&gt;&lt;h4 style="margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left; line-height: 17.999801635742188px;"&gt;&lt;span style="font-size: 8pt;"&gt;CONCLUSION:&lt;/span&gt;&lt;/h4&gt;&lt;p style="margin: 0px 0px 0.5em; line-height: 17.999801635742188px;"&gt;&lt;span style="font-size: 8pt;"&gt;A&amp;nbsp;&lt;span class="highlight"&gt;shortened&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;6-week&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;treatment&lt;/span&gt;&amp;nbsp;with PTNS appears to be successful, with a significant reduction in symptoms and improvement in HRQL. This early data suggest that the duration of&amp;nbsp;&lt;span class="highlight"&gt;treatment&lt;/span&gt;&amp;nbsp;for peripheral neuromodulation can be halved compared with the conventional 12 weeks, which would make it more acceptable and cost effective for patients. A randomised controlled trial of 6 weeks vs 12 weeks of PTNS therapy would be useful in determining the optimal duration of&amp;nbsp;&lt;span class="highlight"&gt;treatment&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Ridout, A.E.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Damodaram, M.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Dadswell, R.
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://www.ncbi.nlm.nih.gov/pubmed/20590544">http://www.ncbi.nlm.nih.gov/pubmed/20590544</a>
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2010.09461.x/epdf">http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2010.09461.x/epdf</a>
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection code Home library Current library Shelving location Date acquired Total Checkouts Date last seen Price effective from Koha item type
        Staff publications for NMDX Ferriman Information and Library Service (North Middlesex) Ferriman Information and Library Service (North Middlesex) Online 07/06/2022   07/06/2022 07/06/2022 UNKNOWN