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Use of plasma human herpesvirus-8 viral load measurement: evaluation of practice in three UK HIV treatment centres (Record no. 76160)

MARC details
000 -LEADER
fixed length control field 02104cam a2200181 4500
001 - CONTROL NUMBER
control field NMDX7171
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 120401t2017 xxu||||| |||| 00| 0 eng d
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name O'Sullivan, A.
240 ## - UNIFORM TITLE
Uniform title <a href="International Journal of STD & AIDS">International Journal of STD & AIDS</a>
245 ## - TITLE STATEMENT
Title Use of plasma human herpesvirus-8 viral load measurement: evaluation of practice in three UK HIV treatment centres
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Date of publication, distribution, etc. 2017
500 ## - GENERAL NOTE
General note NMUH Staff Publications
500 ## - GENERAL NOTE
General note 28
520 ## - SUMMARY, ETC.
Summary, etc. &lt;span style="font-size: 10pt;"&gt;A retrospective audit of&amp;nbsp;&lt;span class="highlight" style="font-family: arial, helvetica, clean, sans-serif;"&gt;plasma&lt;/span&gt;&amp;nbsp;human herpesvirus-8 (HHV-8) viral load testing was performed in three HIV treatment centres over 24 months. Reasons for testing (360 tests) were: symptoms of systemic inflammatory response syndrome (SIRS) (fever, lymphadenopathy and raised inflammatory markers); monitoring in known HHV-8 pathology other than Kaposi sarcoma (KS); investigation of known/suspected KS, and other/no reason. Of patients with multicentric Castleman disease (MCD), 14/16 (88%) had detectable&amp;nbsp;&lt;span class="highlight" style="font-family: arial, helvetica, clean, sans-serif;"&gt;plasma&lt;/span&gt;&amp;nbsp;HHV-8, as did 27/45 (60%) with biopsy proven or clinically confirmed KS, and 6/19 (32%) with lymphoma. Neither of the two patients with MCD and no detectable HHV-8 had SIRS symptoms at the time of the test. There was wide variation between centres in the indications prompting HHV-8 testing, with a more conservative approach resulting in a higher proportion of positive results. Measuring&amp;nbsp;&lt;span class="highlight" style="font-family: arial, helvetica, clean, sans-serif;"&gt;plasma&lt;/span&gt;&amp;nbsp;HHV-8 in the absence of SIRS symptoms, established HHV-8 disease monitoring, or confirmed/suspected KS is unlikely to yield detectable HHV-8 thus allowing potential cost savings.&lt;/span&gt;
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Ainsworth, J.
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://www.ncbi.nlm.nih.gov/pubmed/28120699">https://www.ncbi.nlm.nih.gov/pubmed/28120699</a>
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://journals.sagepub.com/doi/pdf/10.1177/0956462416676031">http://journals.sagepub.com/doi/pdf/10.1177/0956462416676031</a>
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection code Home library Current library Shelving location Date acquired Total Checkouts Date last seen Price effective from Koha item type
        Staff publications for NMDX Ferriman Information and Library Service (North Middlesex) Ferriman Information and Library Service (North Middlesex) Online 07/06/2022   07/06/2022 07/06/2022 UNKNOWN