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Nanoparticles and brain tumor treatment (Record no. 90791)

MARC details
000 -LEADER
fixed length control field 06399cam a2201057Ia 4500
001 - CONTROL NUMBER
control field ocn811139143
003 - CONTROL NUMBER IDENTIFIER
control field OCoLC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240729130944.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION
fixed length control field m e d
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr cn||||m|||a
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 120926s2012 nyua foab 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency CaBNvSL
019 ## -
-- 843077259
-- 858681730
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9781606504086
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 1606504088
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9781606504222
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 1606504223
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 1283896060
Qualifying information (ebk)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9781283896061
Qualifying information (ebk)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 9780791860038
Qualifying information (print)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 0791860035
Qualifying information (print)
028 52 - PUBLISHER NUMBER
Publisher number 860038
Source asme
035 ## - SYSTEM CONTROL NUMBER
System control number 501120
-- (N$T)
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC)811139143
Canceled/invalid control number (OCoLC)843077259
-- (OCoLC)858681730
060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER
Classification number 2013 A-196
060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER
Classification number WL 358
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED
Subject category code subdivision 108000
Source bisacsh
049 ## - LOCAL HOLDINGS (OCLC)
Holding library MAIN
245 00 - TITLE STATEMENT
Title Nanoparticles and brain tumor treatment
Statement of responsibility, etc
Medium [E-Book]
246 1# - VARIANT TITLE
Title Application of nanoparticles in brain tumor treatment
260 ## - PUBLICATION INFORMATION
Place of publication New York, N.Y. :
Publisher ASME ;
Place of publication [New York, N.Y.] (222 East 46th Street, New York, NY 10017) :
Publisher Momentum Press,
Date 2012.
300 ## - PHYSICAL DESCRIPTION
Physical description 1 online resource (viii, 99 pages) :
Other physical details illustrations
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
490 1# - SERIES TITLE
Series statement Biomedical and nanomedical technologies
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes bibliographical references (pages 81-99).
505 0# - CONTENTS
Contents 1. Introduction.
505 8# - CONTENTS
Contents 2. Glioma biology -- 2.1 Invasion and angiogenesis.
505 8# - CONTENTS
Contents 3. Blood-brain barrier -- 3.1 Blood-brain barrier physiology -- 3.2 Blood-brain barrier transport systems.
505 8# - CONTENTS
Contents 4. Nanomedicine and nanotechnology -- 4.1 Nanoparticle drug delivery -- 4.1.1 Nanoparticle distribution -- 4.1.2 Nanoparticle functionalization -- 4.1.3 Nanoparticle targeting -- 4.2 Nanomedicine and cancer -- 4.3 Nanomedicine and toxicity.
505 8# - CONTENTS
Contents 5. Nanoparticle technologies -- 5.1 Polymeric and polymer-drug conjugate nanoparticles -- 5.2 Micelle nanoparticles -- 5.3 Liposomes -- 5.4 Gold and silver nanoparticles -- 5.5 Metal oxide -- 5.6 Magnetic nanoparticles -- 5.7 Carbon nanotubes -- 5.8 Fullerenes -- 5.9 Peptides nanoparticles -- 5.10 Silica nanoparticles -- 5.11 Quantum dots -- 5.12 Dendrimers.
505 8# - CONTENTS
Contents 6. Nanomedicine applications in brain tumors -- 6.1 Brain tumor drug targeting -- 6.1.1 Systemic approaches -- 6.1.2 Physiological approaches -- 6.1.2.1 Receptor-mediated transcytosis -- 6.1.2.2 Adsorptive-mediated transcytosis -- 6.1.2.3 Efflux pump inhibition -- 6.1.2.4 Cell-mediated drug transport -- 6.1.3 Direct CNS approaches -- 6.1.3.1 Intracerebral routes -- 6.1.4 Drug modifications and prodrugs.
505 8# - CONTENTS
Contents 7. Experimental studies.
505 8# - CONTENTS
Contents 8. Conclusions -- References.
520 3# - ABSTRACT
Abstract Despite progresses in surgery, radiotherapy, and in chemotherapy, an effective curative treatment of gliomas does not yet exist. Mortality is still close to 100% and the average survival of patients with GBM is less than 1 year. The efficacy of current anti-cancer strategies in brain tumors is limited by the lack of specific therapies against malignant cells. Besides, the delivery of the drugs to brain tumors is limited by the presence of the blood brain barrier. The oncogenesis of gliomas is characterized by several biological processes and genetic alterations, involved in the neoplastic transformation. The modulation of gene expression to more levels, such as DNA, mRNA, proteins and transduction signal pathways, may be the most effective modality to down-regulate or silence some specific gene functions. Gliomas are characterized by extensive microvascular proliferation and a higher degree of vasculature. In malignant gliomas targeted therapies efficacy is low. In this complex field, it seems to be very important to improve specific selective drugs delivery systems. Drugs, antisense oligonucleotides, small interference RNAs, engineered monoclonal antibodies and other therapeutic molecules may diffuse into CNS overcoming the BBB. Nanotechnology could be used both to improve the treatment efficacy and to reduce the adverse side effects.
590 ## - LOCAL NOTE (RLIN)
Local note WorldCat record variable field(s) change: 650
650 #0 - SUBJECT HEADINGS
Subject term Nanomedicine.
650 #0 - SUBJECT HEADINGS
Subject term Nanoparticles.
650 #0 - SUBJECT HEADINGS
Subject term Brain
General subdivision Tumors
-- Treatment.
650 #0 - SUBJECT HEADINGS
Subject term Nanotechnology.
650 #2 - SUBJECT HEADINGS
Subject term Brain Neoplasms
General subdivision therapy
650 #2 - SUBJECT HEADINGS
Subject term Nanomedicine
650 #2 - SUBJECT HEADINGS
Subject term Nanoparticles
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Nanomedicine
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Nanotechnology
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Nanoparticles
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Nanoparticles in Brain Tumor Treatment
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Nanoparticle Drug Delivery
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Nanoparticle Targeting
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Blood-Brain Barrier
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Glioma
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Astrocytoma
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Glioblastoma
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Brain Tumor
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Glioma Treatment
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Brain Tumor Drug Targeting
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Angiogenesis
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Polymeric
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Nanoparticles and Brain Tumors
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Carbon Nanotubes and Brain Tumors
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Fullerenes and Brain Tumors
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Silica Nanoparticles and Brain Tumors
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Micelle Nanoparticles and Brain Tumors
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Liposome and Brain Tumors
700 1# - ADDED PERSONAL NAME
Added personal author Caruso, Gerardo.
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Biomedical & nanomedical technologies.
856 ## - ONLINE RESOURCE
Uniform Resource Identifier <a href="#gotoholdings">#gotoholdings</a>
Link text Access resource
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Suppress in OPAC Do not Suppress in OPAC
588 0# - SOURCE OF DESCRIPTION NOTE
Source of description note Online resource; title from PDF title page (Momentum Press, viewed April 12, 2013).
938 ## -
-- Coutts Information Services
-- COUT
-- 24444258
938 ## -
-- ebrary
-- EBRY
-- ebr10605115
938 ## -
-- EBSCOhost
-- EBSC
-- 501120
938 ## -
-- ProQuest MyiLibrary Digital eBook Collection
-- IDEB
-- cis24444258
938 ## -
-- Momentum Press
-- NYMP
-- 9781606504222
938 ## -
-- YBP Library Services
-- YANK
-- 9728798
938 ## -
-- YBP Library Services
-- YANK
-- 11669335
994 ## -
-- 92
-- N$T
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Source of acquisition Total Checkouts Date last seen Uniform Resource Identifier Price effective from Koha item type
        Stenhouse Library (Kingston Hospital) Stenhouse Library (Kingston Hospital) Online 28/11/2022 eBook EBSCO clinical collection   28/11/2022 https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=501120 28/11/2022 Electronic book
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