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Cancer stem cells : (Record no. 92456)

MARC details
000 -LEADER
fixed length control field 04264cam a2200637Ki 4500
001 - CONTROL NUMBER
control field ocn953735250
003 - CONTROL NUMBER IDENTIFIER
control field OCoLC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240729132045.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION
fixed length control field m d
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr cnu---unuuu
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160719s2016 maua ob 001 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency N$T
019 ## -
-- 961933973
-- 980620268
-- 1005112732
-- 1005326093
-- 1007388634
-- 1036280850
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9780674969582
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 0674969588
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 9780674088740
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 0674088743
035 ## - SYSTEM CONTROL NUMBER
System control number 1287333
-- (N$T)
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC)953735250
Canceled/invalid control number (OCoLC)961933973
-- (OCoLC)980620268
-- (OCoLC)1005112732
-- (OCoLC)1005326093
-- (OCoLC)1007388634
-- (OCoLC)1036280850
060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER
Classification number QZ 266
072 #7 - SUBJECT CATEGORY CODE
Subject category code HEA
Subject category code subdivision 039000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED
Subject category code subdivision 014000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED
Subject category code subdivision 022000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED
Subject category code subdivision 112000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED
Subject category code subdivision 045000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI
Subject category code subdivision 017000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI
Subject category code subdivision 075000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED
Subject category code subdivision 062000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI
Subject category code subdivision 034000
Source bisacsh
049 ## - LOCAL HOLDINGS (OCLC)
Holding library MAIN
100 1# - MAIN ENTRY--PERSONAL NAME
Personal author Laplane, Lucie,
Relator term author.
245 10 - TITLE STATEMENT
Title Cancer stem cells :
Subtitle philosophy and therapies
Statement of responsibility, etc
Medium [E-Book]
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Cambridge, Massachusetts :
Name of producer, publisher, distributor, manufacturer Harvard University Press,
Date of production, publication, distribution, manufacture, or copyright notice 2016.
300 ## - PHYSICAL DESCRIPTION
Physical description 1 online resource (x, 252 pages) :
Other physical details illustrations
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes bibliographical references and index.
505 0# - CONTENTS
Contents Part I. Cancer stem cells: a new theory of cancer -- Cancer stem cells' triumph -- The CSC theory -- Part II. The historical emergence of the CSC concept and its driving role in cancers -- Teratocarcinomas and embryonic stem cells -- Leukemic and hematopoietic stem cells -- Part III. Debates on CSCs and stem cells: what are they? -- Origin, stemness, and stem cells: the meaning of words -- Stem cell identity -- Part IV. The identity of stemness and its consequences for cancer therapies -- If stemness is a categorical or a dispositional property, how can we cure cancers? -- If stemness is a relational or systemic property, how can we cure cancer?
520 ## - ABSTRACT
Abstract "An innovative theory proposes a new therapeutic strategy to break the stalemate in the war on cancer. It is called cancer stem cell (CSC) theory, and Lucie Laplane offers a comprehensive analysis, based on an original interdisciplinary approach that combines biology, biomedical history, and philosophy. Rather than treat cancer by aggressively trying to eliminate all cancerous cells--with harmful side-effects for patients--CSC theory suggests the possibility of targeting the CSCs, a small fraction of cells that lie at the root of cancers. CSCs are cancer cells that also have the defining properties of stem cells--the abilities to self-renew and to differentiate. According to this theory, only CSCs and no other cancer cells can induce tumor formation. To date, researchers have not agreed on the defining feature of CSCs--their stemness. Drawing from a philosophical perspective, Laplane shows that there are four possible ways to understand this property: stemness can be categorical (an intrinsic property of stem cells), dispositional (an intrinsic property whose expression depends on external stimuli), relational (an extrinsic property determined by a cell's relationship with the microenvironment), or systemic (an extrinsic property controlled at the system level). Our ability to cure cancers may well depend upon determining how these definitions apply to different types of cancers."--Provided by publisher.
590 ## - LOCAL NOTE (RLIN)
Local note Master record variable field(s) change: 072
650 #0 - SUBJECT HEADINGS
Subject term Cancer cells.
650 #0 - SUBJECT HEADINGS
Subject term Stem cells.
650 #0 - SUBJECT HEADINGS
Subject term Cancer
General subdivision Treatment
-- Philosophy.
650 #0 - SUBJECT HEADINGS
Subject term Oncology.
9 (RLIN) 13364
650 12 - SUBJECT HEADINGS
Subject term Neoplastic Stem Cells.
650 22 - SUBJECT HEADINGS
Subject term Stem Cells.
650 22 - SUBJECT HEADINGS
Subject term Neoplasms
General subdivision therapy.
856 ## - ONLINE RESOURCE
Uniform Resource Identifier <a href="#gotoholdings">#gotoholdings</a>
Link text Access resource
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Suppress in OPAC Do not Suppress in OPAC
588 0# - SOURCE OF DESCRIPTION NOTE
Source of description note Print version record.
938 ## -
-- EBSCOhost
-- EBSC
-- 1287333
938 ## -
-- YBP Library Services
-- YANK
-- 12758812
994 ## -
-- 92
-- N$T
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Source of acquisition Total Checkouts Date last seen Uniform Resource Identifier Price effective from Koha item type
        Stenhouse Library (Kingston Hospital) Stenhouse Library (Kingston Hospital) Online 28/11/2022 eBook EBSCO clinical collection   28/11/2022 https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=1287333 28/11/2022 Electronic book
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