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A complex systems approach to epilepsy : (Record no. 98399)

MARC details
000 -LEADER
fixed length control field 02430nam a22002897a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 240201b2023 |||||||| |||| 00| 0 eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9781009258081
Qualifying information (hardback)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 9781108582285
Qualifying information (epub)
040 ## - CATALOGING SOURCE
Original cataloging agency DNLM/DLC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
042 ## - AUTHENTICATION CODE
Authentication code pcc
060 00 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER
Classification number WL 385
245 02 - TITLE STATEMENT
Title A complex systems approach to epilepsy :
Subtitle concept, practice and therapy /
Statement of responsibility, etc edited by Rodney C. Scott, J. Matthew Mahoney.
260 ## - PUBLICATION INFORMATION
Place of publication Cambridge ;
Publisher Cambridge University Press,
Date 2023.
300 ## - PHYSICAL DESCRIPTION
Physical description vii, 160p :
Other physical details ill. ;
Dimensions 26cm.
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes bibliographical references and index.
505 0# - CONTENTS
Contents Introduction -- Systems biology approaches to the genetic complexity of epilepsy -- Transcriptomic and epigenomic approaches for epilepsy -- Phenomenological mesoscopic models for seizure activity -- Personalized network modeling in epilepsy -- The baseline and epileptiform EEG : a complex systems approach -- Neuronal approaches to epilepsy -- Mapping epileptic networks with scalp and invasive EEG : applications to epileptogenic zone localization and seizure prediction -- A neuroimaging network-level approach to drug-resistant epilepsy -- Epilepsy as a complex network disorder: insights from functional MRI.
520 ## - ABSTRACT
Abstract The epilepsies are devastating neurological disorders for which progress developing effective new therapies has slowed over recent decades, primarily due to the complexity of the brain at all scales. This reality has shifted the focus of experimental and clinical practice toward complex systems approaches to overcoming current barriers. Organized by scale from genes to whole brain, the chapters of this book survey the theoretical underpinnings and use of network and dynamical systems approaches to interpreting and modeling experimental and clinical data in epilepsy. The emphasis throughout is on the value of the non-trivial, and often counterintuitive, properties of complex systems, and how to leverage these properties to elaborate mechanisms of epilepsy and develop new therapies. In this essential book, readers will learn key concepts of complex systems theory applied across multiple scales and how each of these scales connects to epilepsy.
650 12 - SUBJECT HEADINGS
Subject term Epilepsy
650 12 - SUBJECT HEADINGS
Subject term Systems Analysis
650 22 - SUBJECT HEADINGS
Subject term Systems Biology
700 1# - ADDED PERSONAL NAME
Added personal author Scott, Rod,
Relator term editor.
700 1# - ADDED PERSONAL NAME
Added personal author Mahoney, J. Matthew,
Relator term editor.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Suppress in OPAC Do not Suppress in OPAC
263 ## - PROJECTED PUBLICATION DATE
Projected publication date 2208
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
    National Library of Medicine     Whittington Health Library Whittington Health Library Shelves 01/02/2024   WL 385 SCO 00024600 01/02/2024 01/02/2024 Book
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