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Mantle cell lymphoma masquerading as chalazia, a case report

By: Publication details: 2016Uniform titles:
  • Expert Review of Ophthalmology
Online resources: Summary: <span style="font-size: 10pt;">Objective: A chalazion is one of the most common presentations in ophthalmology practice and is often diagnosed and managed in busy, one-stop surgical clinics by junior doctors and allied health professionals.Methods: Case note review of a patient with mantle cell lymphoma masquerading as chalazia.Results: We report a case of a Caucasian 65 year-old male presenting with a 1-year history of bilateral lower eyelid swellings, diagnosed as chalazia by his general practitioner, which turned out to be mantle cell lymphoma. Mantle cell lymphoma is a type of non-Hodgkin lymphoma associated with significant morbidity and mortality. The patient was staged as IVa and responded well to chemotherapy.Conclusion: Mantle cell lymphoma in the ocular adnexa is rare but potentially fatal and this is the first report of mantle cell lymphoma presenting as chalazia in the literature. Ophthalmologists and allied health professionals should include this in the differential diagnosis of persistent eyelid swelling and always consider biopsy of any lesion with an atypical history or unusual findings on clinical examination.&nbsp;</span>
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NMUH Staff Publications

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&lt;span style="font-size: 10pt;"&gt;Objective: A chalazion is one of the most common presentations in ophthalmology practice and is often diagnosed and managed in busy, one-stop surgical clinics by junior doctors and allied health professionals.Methods: Case note review of a patient with mantle cell lymphoma masquerading as chalazia.Results: We report a case of a Caucasian 65 year-old male presenting with a 1-year history of bilateral lower eyelid swellings, diagnosed as chalazia by his general practitioner, which turned out to be mantle cell lymphoma. Mantle cell lymphoma is a type of non-Hodgkin lymphoma associated with significant morbidity and mortality. The patient was staged as IVa and responded well to chemotherapy.Conclusion: Mantle cell lymphoma in the ocular adnexa is rare but potentially fatal and this is the first report of mantle cell lymphoma presenting as chalazia in the literature. Ophthalmologists and allied health professionals should include this in the differential diagnosis of persistent eyelid swelling and always consider biopsy of any lesion with an atypical history or unusual findings on clinical examination.&amp;nbsp;&lt;/span&gt;

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