Transfusion and transplantation science

Basic Immunology -- Human Erythrocyte Antigens or Blood groups -- Donors and Donations: Collection and processing -- Blood Donation Testing -- Clinical Use of Blood Components -- Compatibility testing and adverse effects -- Immune Red Cell Destruction -- Human Leucocyte Antigens (HLA) and Their Clinical Significance -- Human Platelet Antigens (HPA) and Human Neutrophil Antigens (HNA) and Their Clinical Significance -- Haemopoietic Stem Cell Banking -- Tissue Banking -- Quality Issues;

Includes bibliographical references and index.

Biomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible. The Fundamentals of Biomedical Science series is written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis. Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed - from microbiology to cytopathology to transfusion science. Alongside volumes exploring specific biomedical themes and related laboratory diagnosis, an overarching Biomedical Science Practice volume gives a grounding in the professional and experimental skills with which any Biomedical Scientist must be equipped.The series: * Understands the complex roles of Biomedical Scientists in the modern practice of medicine * Understands the development needs of employers and the Profession * Addresses the need for understanding of a range of fundamental sciences in the context of Biomedicine * Places the theoretical aspects of Biomedical Science in their practical context The science of transfusion and transplantation demands a multifaceted understanding of immunology, haematology, and genetics from the biomedical scientist. Transfusion and Transplantation Science coherently synthesises the essential concepts of these subjects and presents them within the practical framework of the hospital banking and transplantation centre, thereby furnishing the reader with the knowledge and skills required to specialize in this discipline. Beginning with an overview of potential immune responses to transfusion and transplantation, the text goes on to explain the aetiology behind these responses with a view to the prediction, diagnosis, and mitigation of adverse effects on the patient.It then outlines issues of quality, but also regulatory and legal concerns, that need to be considered when collecting, preparing, and storing products for transfusion or transplantation.