Image from Google Jackets

Handbook for clinical research : design, statistics, and implementation [E-Book]

Contributor(s):

Publisher: New York, NY : Demos Medical Publishing, LLC, [2015]Description: 1 online resource (xiv, 332 pages .)Content type:

text

Media type:

computer

Carrier type:

online resource

ISBN:

1617050997
9781617050992

Subject(s):

NLM classification:

W 20.5

Online resources:

Access resource

Contents:

Machine generated contents note: pt. I DESIGN -- 1.Development and Testing of Treatments / John Whyte -- 2.Qualitative Research / Elena Gillespie -- 3.Single-Case Experimental Designs / Michael Perdices -- 4.Studies of Associations / Michael Schonberger -- 5.Observational Studies: Retrospective Versus Prospective / Katherine W. Stenson -- 6.Historical Controls / Katherine W. Stenson -- 7.Subject as Own Control / Lisa A. Lombard -- 8.Longitudinal Cohort Versus Cross-Sectional Cohort Studies / Katherine W. Stenson -- 9.Survey Research / Amanda Leigh Harrington -- 10.Choice of Control Groups in Treatment Studies / Sureyya S. Dikmen -- 11.Randomization / Emilia Bagiella -- 12.Special Issues in Randomized Controlled Trials / Michael L. Boninger -- 13.Secondary Data Analysis / Amol Karmarkar -- 14.Scoping Study / Xinsheng Cai -- 15.Systematic Reviews / Xinsheng Cai -- 16.Meta-Analysis / Xinsheng Cai -- 17.Recommendations for Reporting Research Studies / Ronald T. Seel

Note continued: 18.Developing and Evaluating Systematic Reviews and Practice Guidelines / Ronald T. Seel -- pt. II STATISTICS -- 19.Introduction / Christopher J. Swearingen -- 20.Types of Data / Marcus Wellen -- 21.Descriptive Statistics / Todd G. Nick -- 22.Data Distributions / Marcus Wellen -- 23.Samples and Populations / Marcus Wellen -- 24.Visual Display of Data / Marcus Wellen -- 25.Data Cleaning / Jingyun Li -- 26.Missing Data and Imputation / Christopher J. Swearingen -- 27.Estimation / Mallikarjuna Rettiganti -- 28.Hypothesis Testing / Mallikarjuna Rettiganti -- 29.Sample Size and Power / Mallikarjuna Rettiganti -- 30.Comparing Matched Samples With Continuous-Type Outcomes: Two Groups / Ming Li -- 31.Comparing Independent Samples With Continuous-Type Outcomes: Two Groups / Ming Li -- 32.Comparing Independent Samples for Continuous-Type Outcomes: Three Groups or More / Ming Li -- 33.Correlation / Christopher J. Swearingen

Note continued: 34.Simple Linear Regression / Christopher J. Swearingen -- 35.Multiple Linear Regression / Christopher J. Swearingen -- 36.Longitudinal and Clustered Data / Mallikarjuna Rettiganti -- 37.Significance Tests: Categorical Data / Xinyu Tang -- 38.Measures of Effect Sizes for Categorical Outcomes / Todd G. Nick -- 39.Logistic Regression / Chunqiao Luo -- 40.Kaplan-Meier Estimator / Xinyu Tang -- 41.Log-Rank Test / Xinyu Tang -- 42.Proportional Hazards Model / Xinyu Tang -- 43.Sources of Error: Selection Bias, Information Bias, and Confounding / Laura Smith -- 44.Mediation Analyses / Todd G. Nick -- 45.Epidemiology Study: Incidence and Prevalence / Laura Smith -- 46.Validity and Performance of Screening: Sensitivity, Specificity, Positive Predictive Value, and Negative Predictive Value / Laura Smith -- 47.Statistical Tools for Agreement and Reliability Studies / Shasha Bai -- 48.Classical Test Theory / Jamie Reilly -- 49.Item Response Theory / Jamie Reilly

Note continued: pt. III IMPLEMENTATION -- Grant Proposals -- 50.Successful Grant Applications / Flora M. Hammond -- 51.Sources of Research Funding / James F. Malec -- 52.Planning Grants / Eric Lenze -- 53.Developing the Idea With Stakeholder Input / John D. Corrigan -- 54.Research Questions, Hypotheses, Aims, and Abstract / Flora M. Hammond -- 55.Reviewing the Literature / Edward Garay -- 56.Background and Significance / Flora M. Hammond -- 57.Preliminary Studies and Experience / Flora M. Hammond -- 58.Methods and Design / Kathleen R. Bell -- 59.Types of Measures / James F. Malec -- 60.Letters of Support / James F. Malec -- 61.Budget and Budget Justification / Rob Dimmitt -- 62.Preaward Management / Rob Dimmitt -- Conducting the Research -- 63.Post-Award Management / LaMoria Patterson -- 64.Good Clinical Practices / John R. Baumann -- 65.Research Misconduct / Rebecca Hopson -- 66.Study Protocol / Flora M. Hammond -- 67.Manual of Procedures / Flora M. Hammond

Note continued: 68.Treatment Manuals / Kathleen R. Bell -- 69.Participant Recruitment and Enrollment / Flora M. Hammond -- 70.Participant Retention / Flora M. Hammond -- 71.Data Collection / Flora M. Hammond -- 72.Case Report Forms / Flora M. Hammond -- 73.Database Development / Emilia Bagiella -- 74.Data Dictionary / Emilia Bagiella -- 75.Data Management / Emilia Bagiella -- 76.Plan of Operation / Angelle M. Sander -- 77.Evaluation / Angelle M. Sander -- 78.Regulatory Binder and Essentia Documents / Flora M. Hammond -- 79.Adverse Events / Flora M. Hammond -- 80.Protocol Deviations and Violations / Flora M. Hammond -- 81.Data and Safety Monitoring / Emilia Bagiella -- 82.Multicenter Trials / Flora M. Hammond -- 83.Site Monitoring and Oversight / Flora M. Hammond.

Summary: With over 80 information-packed chapters, Handbook for Clinical Research delivers the practical insights and expert tips necessary for successful research design, analysis, and implementation. Using clear language and accessible bullet point format, the authors present the knowledge and expertise developed over time and traditionally shared from mentor to mentee and colleague to colleague. Organized for quick access to key topics and replete with practical examples, the book describes a variety of research designs and statistical methods and explains how to choose the best design for a particular project. Research implementation, including regulatory issues and grant writing is also covered. The book opens with a section on the basics of research design, discussing the many ways in which studies can be organized, executed, and evaluated. The second section is devoted to statistics; it explains how to choose the correct statistical approach and reviews the varieties of data types, descriptive and inferential statistics, methods for demonstrating associations, hypothesis testing and prediction, specialized methods, and considerations in epidemiological studies and measure construction. The third section covers implementation, including how to develop a grant application step by step, the project budget, and the nuts and bolts of the timely and successful completion of a research project and documentation of findings; procedural manuals and case report forms; collecting, managing, and securing data; operational structure and ongoing monitoring and evaluation; and ethical and regulatory concerns in research with human subjects. With a concise presentation of the essentials for successful research, the Handbook for Clinical Research is a valuable addition to the library of any student, researcher, professional, or clinician interested in expanding the knowledge base of his or her field.

Holdings
Item type	Home library	Class number	URL	Status	Date due	Barcode
Electronic book	Stenhouse Library (Kingston Hospital) Online		Link to resource	Available

Includes bibliographical references and index.

Print version record.

With over 80 information-packed chapters, Handbook for Clinical Research delivers the practical insights and expert tips necessary for successful research design, analysis, and implementation. Using clear language and accessible bullet point format, the authors present the knowledge and expertise developed over time and traditionally shared from mentor to mentee and colleague to colleague. Organized for quick access to key topics and replete with practical examples, the book describes a variety of research designs and statistical methods and explains how to choose the best design for a particular project. Research implementation, including regulatory issues and grant writing is also covered. The book opens with a section on the basics of research design, discussing the many ways in which studies can be organized, executed, and evaluated. The second section is devoted to statistics; it explains how to choose the correct statistical approach and reviews the varieties of data types, descriptive and inferential statistics, methods for demonstrating associations, hypothesis testing and prediction, specialized methods, and considerations in epidemiological studies and measure construction. The third section covers implementation, including how to develop a grant application step by step, the project budget, and the nuts and bolts of the timely and successful completion of a research project and documentation of findings; procedural manuals and case report forms; collecting, managing, and securing data; operational structure and ongoing monitoring and evaluation; and ethical and regulatory concerns in research with human subjects. With a concise presentation of the essentials for successful research, the Handbook for Clinical Research is a valuable addition to the library of any student, researcher, professional, or clinician interested in expanding the knowledge base of his or her field.

WorldCat record variable field(s) change: 650

There are no comments on this title.

to post a comment.

Storage	Name	Value	Expiration	Description
Cookie	CGISESSID	Session ID	Until logout or end of session	Session cookie
Cookie	KohaOpacLanguage	Language code	3 years	Stores the language the user selected, so the online catalog will appear in that same language the next time it is visited.
Cookie	form_serialized form_serialized_limits	Search terms and limits	End of session or when the advanced search page is accessed again.	jQuery cookie. Stores search terms and limits of the last advanced search. Set when an advanced search is submitted.
Cookie	search_path_code	ads (fewer) or exs (more)	End of session or when the advanced search page is accessed again.	jQuery cookie. Related to serialized_form* cookies. Stores if the advanced search form was used with 'More options' or 'Fewer options'.
Cookie	num_paragraph	Count of search options added	End of session or when the advanced search page is accessed again.	jQuery cookie. Used to store the number of created options when user selects 'More options' in advanced search to increase search boxes.
Cookie	bib_list	List of record IDs (biblionumbers) separated by /	End of session or until the cart is emptied.	Stores cart contents in the online catalog. Set when records are added to the cart for the first time.