Immunity [E-Book]

Includes bibliographical references (pages 243-248) and index.

Print version record.

Part 1. Immunology. Defense and Danger -- Tracing an Immune Response -- The Laws of Immunology: Universality, Tolerance, and Appropriateness -- Growing Up and Learning Immunology.

Part 2. The First Law: Universality. Vaccines and Serum Therapy -- How Is Specificity Achieved? -- Immunology's "Eureka": Clonal Selection -- How Does Each Lymphocyte Develop a Distinct Receptor? -- B Cells and T Cells Recognize Different Types of Antigens -- My Foray into the Specificity Problem -- Genes And Immune Response -- The Laboratory of Immunology and the T-Cell Receptor.

Part 3. The Second Law: Tolerance -- What Is Tolerance? -- How Does Tolerance Develop? -- Regulatory T Cells and the Prevention of Autoimmunity.

Part 4. The Third Law: Appropriateness -- Different Structures, Different Functions -- Specific Types of Infections, Specific Types of T-Cell Responses -- Our Discovery of IL-4 and the Cells That Make It -- CD8 T Cells: Killer Cells and Friends -- Dendritic Cells: The Cells That Interpret the Infectious Threat.

Part 5. How Did The Immune System Evolve? -- An "Ancient" Immune Response Controls "Modern" Immunity -- The Microbiome and Innate Immunity -- Evolution of the Immune System and Innate Lymphoid Cells.

Part 6. AIDS, Autoimmunity, Allergy, Cancer, and Transplantation -- The HIV Epidemic and the Office Of AIDS Research -- How the Immune System Causes Rheumatoid Arthritis and Lupus -- Allergy and Asthma -- Interleukin-4 and Allergy -- Can the Immune System Control Cancer? -- New Parts for Old: Bone Marrow and Organ Transplantation -- Julien.

Master record variable field(s) change: 050