Acute myeloid leukemia : signssymptoms, classification, and treatment options [E-Book]

Includes bibliographical references and index.

Description based on print version record.

ACUTE MYELOID LEUKEMIA SIGNS/SYMPTOMS, CLASSIFICATION AND TREATMENT OPTIONS ; ACUTE MYELOID LEUKEMIA SIGNS/SYMPTOMS, CLASSIFICATION AND TREATMENT OPTIONS ; Library of Congress Cataloging-in-Publication Data; CONTENTS ; PREFACE ; Chapter 1 CLINICAL PRESENTATION OF ACUTE MYELOID LEUKEMIA ; ABSTRACT ; INTRODUCTION ; INCIDENCE AND PATIENT CHARACTERISTICS ; SYMPTOMS ; ORGAN INVOLVEMENT ; Skin ; Ocular ; Oral ; Central Nervous System ; Cardiovascular ; Pulmonary ; Gastrointestinal ; Lymphoreticular ; Musculoskeletal ; LABORATORY FINDINGS ; Complete Blood Counts ; Coagulation Studies

Electrolytes Leukocyte Larceny ; CLINICAL SYNDROMES ASSOCIATED WITH AML; Leukostasis ; Disseminated Intravascular Coagulation ; Tumor Lysis Syndrome ; Infection ; Extramedullary Disease ; CONCLUSION ; REFERENCES ; Chapter 2 PROGNOSIS OF CORE-BINDING FACTOR ACUTE MYELOID LEUKEMIA ; ABSTRACT ; INTRODUCTION ; Subtypes of CBF AML ; Clinical Prognostic Factors ; Molecular Prognostic Factors ; Cytogenetic Factors ; Minimal Residual Disease ; Other Factors ; CONCLUSION AND FUTURE PERSPECTIVES ; ACKNOWLEDGMENTS; REFERENCES; Chapter 3 PHILADELPHIA CHROMOSOME-POSITIVE ACUTE MYELOID LEUKEMIA

ABSTRACT INTRODUCTION; Differentiating from Blast Phase Chronic Myeloid Leukemia ; ClinicopathologicFeatures ; Management ; Role of Chemotherapy ; Role of Tyrosine Kinase Inhibitors ; Allogeneic Stem Cell Transplantation ; Presence of Additional Abnormalities ; CONCLUSION ; CONFLICT OF INTEREST ; ACKNOWLEDGMENT ; REFERENCES ; Chapter 4 THERAPY OF OLDER PATIENTS WITH ACUTE MYELOID LEUKEMIA; ABSTRACT ; INTRODUCTION ; PROGNOSTIC FACTORS; Patient-Related Prognostic Factors ; Age ; Performance Status ; Comorbidities ; Other Patient-Related Prognostic Factors; Disease-Related Prognostic Factors

WBC Count Cytogenetics ; Molecular Genetics ; Mutations ; Overexpression ; Multidrug Resistance ; Secondary AML ; Other Disease Related Prognostic Factors ; Response-Related Prognostic Factors ; TREATMENT ; Intensive Induction Chemotherapy; The Role of Cytarabine ; The Role of Anthracycline ; The Role of Other Cytotoxic Agents ; The Role of Gemtuzumab Ozogamicin ; The Role of Multidrug Resistance Modulators ; The Role of Growth Factors ; Non-Intensive Induction Chemotherapy ; The Role of BSC ; The Role of Low Dose Cytarabine (LDAC) ; The Role of Clofarabine

The Role of Hypomethylating Agents Azacitidine ; Decitabine ; Postremission Chemotherapy ; CONCLUSION; REFERENCES ; INDEX

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