The beginnings of perinatal medicine [E-Book]

Includes bibliographical references at the end of each chapters and indexes.

Online resource; title from PDF title page (ebrary, viewed February 11, 2015).

1 Preface and introduction; 2 Fetal heart activity and measurements of labor activities; 2.1 Scientific precursors; 2.1.1 Development of the stethoscope; 2.1.2 Recognition of the existence of fetal heart sounds; 2.1.3 First attempts to register the fetal heart beats; 2.1.4 Measurement of the intrauterine pressure during labor; 2.2 Early stages: "modern" cardiotocogram (CTG); 2.3 Later developments; 3 Fetal blood analysis (FBA); 3.1 Precursors; 3.2 Fetal blood analysis (FBA); 3.3 Further developments; 3.3.1 Pulse oxymetry.

3.4 Excursion: Physiological concepts in connection with fetal blood analysis3.4.1 "Brain sparing effect"; 3.4.2 "Maternogenic" increase of metabolic acidity in the fetus; 4 Amniotic fluid interventions and examinations; 4.1 Knowledge about the significance of meconium in the amniotic fluid; 4.2 Amniocentesis; 4.3 Amnioscopy; 5 Prevention of Rh-immunization; 5.1 History; 5.1.1 First descriptions and discovery of the pathogenesis; 5.1.2 First exchange transfusions; 5.2 Attempts to affect the immune system; 5.3 Intrauterine transfusion; 5.4 Rh-immune prophylaxis; 5.5 Later developments.

6 Sonography6.1 Ian Donald -- Pioneer of ultrasound in obstetrics and gynecology; 6.2 Parallel early developments in the USA, Japan, and Russia; 6.3 The ultrasonic boom in the 1960s; 6.3.1 The development and use of new ultrasound devices: the Vidoson real-time scanner and articulated-armcompound contact scanner SSD-; 6.3.2 The work of Alfred Kratochwil; 6.3.3 The Kossoff group: first use of ultrasound in the diagnosis of fetal malformation and further technical innovations; 6.3.4 Ultrasound in the diagnostics of pregnancy assessment; 6.4 The implementation of Doppler ultrasound.

6.5 Later developments and future perspectives6.5.1 The founding of the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) and the first journal in this field; 6.5.2 From the scan of fetal movements to the diagnosis of fetal well-being due to Doppler ultrasound; 6.5.3 The implementation of 3D ultrasound; 6.5.4 Use of ultrasound in the diagnostics of malformation and preterm delivery; 7 Measures in cases of threatened prematurity; 7.1 Tocolysis; 7.1.1 Introduction; 7.1.2 Medications for tocolysis; 7.1.3 Later developments �a�" tocolysis today; 7.1.4 Conclusions.

7.2 History of induction of lung maturation7.2.1 Antecedent of fetal lung maturation; 7.2.2 Early stages of fetal lung maturation 1940s-1960s; 7.2.3 From 1970s till today; 7.2.4 Conclusion; 8 Diagnosis of genetic defects; 8.1 Introduction; 8.2 Early stages of clinical diagnostics: Fetoscopy versus ultrasound; 8.3 The implementation of amniocentesis (AC); 8.4 The implementation of chorionic villus sampling (CVS); 8.5 Later developments in diagnostics: Ultrasound guided CVS and amniocentesis (AC); 8.6 Alpha-fetoprotein in maternal serum as non-invasive diagnostic tool.

Perinatal medicine came into being during the middle of the 20th century, when human medicine entered the intrauterine space. This book presents in an integrative way the history of the still young speciality. The main emphasis is on the time period up to the early 70swhen the major changes e.g. Cardiotocography took place. Both scientific precursors and later developments are mentioned shortly, when appropriate. Many chapters of this book represent a unique eyewitness report by Prof. Erich Saling, the so-called ""Father of Perinatal Medicine""

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