Sex and Gender Differences in Infection and Treatments for Infectious Diseases [E-Book]

Genetics of sex differences in immunity -- The influence of sex hormones and X chromosome in immune responses -- Sex Differences in HIV Infection -- Chapter 6: Effects of Biological Sex and Pregnancy on SARS-CoV-2 Pathogenesis and Vaccine Outcomes -- Biological sex and pregnancy affect influenza pathogenesis and vaccination -- Sex and gender differences in tuberculosis pathogenesis and treatment outcomes -- Sex-Linked Differences in Malaria Risk Across the Lifespan -- Sex Difference in Amebiasis -- Sex Differential and Non-Specific Effects of Vaccines Over the Life Course -- Immunology of pregnancy and systemic consequences.

This fully revised and significantly expanded second edition examines sex and gender differences in the immune system's response to bacterial, viral, and parasitic infections. The volume discusses both common and distinct molecular mechanisms that mediate these differences and illustrates how responses to vaccines may differ between the sexes and in pregnant individuals. Special emphasis is placed on the interplay between hormones and the immune system in the pathogenesis of HIV, SARS-CoV-2, influenza, malaria, tuberculosis, and amebiasis. This second edition includes completely rewritten chapters as well as all new contents. This book is intended for researchers in academia and industry as well as clinicians in the fields of microbiology, immunology, and pharmacology. By expanding knowledge in sex and gender medicine as a basis for developing personalized treatment strategies, the book contributes to UN Sustainable Development Goals 3 (health and well-being) and 5 (gender equality).