Molecular Imaging of Neurodegenerative Disorders [E-Book]

1. What is neurodegeneration? -- 2. Appropriate Use of Biomarkers in Suspected Neurodegenerative Diseases -- 3. Overview of clinically available radiotracers for imaging in neurodegenerative disorders -- 4. FDG PET Imaging Evaluation of Neurodegenerative Dementias -- 5. Amyloid PET Imaging -- 6. Traits and Trammels of Tau Tracer Imaging -- 7. Dopaminergic nerve terminal imaging across the spectrum of aging, idiopathic rapid eye movement (REM) sleep behavior disorder, parkinsonism and dementia -- 8. Cholinergic Imaging and Dementia -- 9. Neuroinflammation Imaging in Neurodegenerative Diseases -- 10. Synaptic PET imaging in neurodegeneration -- 11. MR Imaging of Neurodegeneration -- 12. PET Quantification and Kinetic Analysis -- 13. Semi-quantitative analysis: software-based imaging interpretation - NEUROSTAT/SPM -- 14. Artificial Intelligence Approaches to the Imaging of Neurodegenerative Diseases -- 15. Molecular Imaging In Pediatric Neurodegenerative Disorders -- 16. Simultaneous PET/MR imaging of dementia -- 17. Case-based Guide for Image Interpretation and Reporting.-.

This book provides a comprehensive review of the role of molecular imaging in neurodegenerative diseases. A growing field, molecular imaging of neurodegeneration is becoming increasingly relevant with an aging population, and this book serves to provide both an introduction to the concept and background of neurodegeneration and an update on the most recent imaging advances. Throughout, chapters will review current applications of neuroimaging in neurodegenerative disorders, like dementia and movement disorders, and increase knowledge of quantification and semi-quantification methods for neuroimaging. Imaging methods such as PET/CT and PET/MR are covered, as well as more advanced technologies like artificial intelligence algorithms and novel radiotracers. Chapters are also intended to improve competency in reporting and interpretation skills with structured information on current practice. The book concludes with a collection of up to date practice cases for the interpretation of neurodegeneration in nuclear medicine imaging. This is an ideal guide for nuclear medicine physicians, neuroradiologists, neurologists, residents, trainees, and related medical professionals caring for patients with neurodegeneration.