Multiple Myeloma - A New Era of Treatment Strategies [electronic resource].

By:

Podar, Klaus

Contributor(s):

Anderson, Kenneth C

Publication details: Sharjah : Bentham Science Publishers, 2012.Description: 1 online resource (217 p.)ISBN:

9781608052974 (electronic bk.)
1608052974 (electronic bk.)

Subject(s):

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Contents:

01 Multiple Myeloma -- A New Era of Treatment Strategies.pdf; 02 Cover Page; 03 REVISED eBooks End User License Agreement-Website; 04 TABLE OF CONTENTS; 05 Foreword; 06 PREFACE; 07 Contributors; 08 Section 1; 09 Chapter 01; 10 Chapter 02; 11 Chapter 03; 12 Section 2; 13 Chapter 04; 14 Chapter 05; 15 Chapter 06; 16 Chapter 07; 17 Chapter 08; 18 Section 3; 19 Chapter 9; 20 Chapter 10; 21 Chapter 11; 22 Section 4; 23 Chapter 12; 24 Chapter 13; 25 INDEX.

Summary: Multiple Myeloma (MM), the second most common blood cancer in adults, is a clonal plasma cell malignancy within the bone marrow characterized by osteolytic bone lesions, renal disease, and immunodeficiency. It is now well established that MM cell- induced disruption of the bone marrow homeostasis between the highly organized cellular and extracellular compartments supports MM cell proliferation, survival, migration, and drug resistance via activation of various signaling pathways. Based on this knowledge, the prototypic drugs thalidomide, bortezomib, and lenalidomide, which target both MM cell.

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Item type	Home library	Class number	URL	Status	Date due	Barcode
Electronic book	Stenhouse Library (Kingston Hospital) Online		Link to resource	Available

Multiple Myeloma (MM), the second most common blood cancer in adults, is a clonal plasma cell malignancy within the bone marrow characterized by osteolytic bone lesions, renal disease, and immunodeficiency. It is now well established that MM cell- induced disruption of the bone marrow homeostasis between the highly organized cellular and extracellular compartments supports MM cell proliferation, survival, migration, and drug resistance via activation of various signaling pathways. Based on this knowledge, the prototypic drugs thalidomide, bortezomib, and lenalidomide, which target both MM cell.

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