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Handbook of depression in Alzheimer's disease [E-Book]

Contributor(s): Series: Advances in Alzheimer's disease (Series) ; volume 4.Publisher: Amsterdam : IOS Press, [2015]Description: 1 online resourceContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9781614995425
  • 1614995427
  • 1614995419
  • 9781614995418
Subject(s): NLM classification:
  • WT 155
Online resources:
Contents:
Title Page; Preface; Contents; Section 1. Phenomenology; Phenomenology of Depression in Alzheimer's Disease; Apathy and Depression in Mild Alzheimer's Disease: A Cross-sectional Study using Diagnostic Criteria; Neuropsychiatric Symptoms in Alzheimer's Disease and Vascular Dementia; Section 2. Epidemiology; Depression in Alzheimer's Disease: Epidemiology, Mechanisms, and Management; Depression and Mild Cognitive Impairment in the General Population: Results of the Heinz Nixdorf Recall Study.
Late-Life Depression as a Risk Factor for Mild Cognitive Impairment or Alzheimer's Disease in 30 US Alzheimer's Disease CentersLatent Classes of Neuropsychiatric Symptoms in NACC Controls and Conversion to Mild Cognitive Impairment or Dementia; Section 3. Neuropsychology; Neuropsychological Functioning in the Acute and Remitted States of Late-Life Depression; Differential Cognitive Deterioration in Dementia: A Two Year Longitudinal Study; Coupled Cognitive and Functional Change in Alzheimer's Disease and the Infl uence of Depressive Symptoms.
Cognition, Gender, and Functional Abilities in Alzheimer's Disease: How are They Related?Gender-Specifi Differences in Cognitive Profiles of Patients with Alzheimer's Disease: Results of the Prospective Dementia Registry Austria (PRODEM-Austria); Section 4. Neurobiology and Neuropathology; Depression and Alzheimer's Disease: Is Stress the Initiating Factor in a Common Neuropathological Cascade?; The Role of Indoleamine 2,3-Dioxygenase in a Mouse Model of Neuroinfl ammation-Induced Depression; Depression and Alzheimer's Disease: Novel Postmortem Brain Studies Reveal a Possible Common Mechanism.
Neuropathology of Depression in Alzheimer's Disease: Current Knowledge and the Potential for New TreatmentsSection 5. Neuroimaging; Depressive Symptoms and Biomarkers of Alzheimer's Disease in Cognitively Normal Older Adults; Hippocampal Volume in Older Adults at Risk of Cognitive Decline: The Role of Sleep, Vascular Risk, and Depression; Depressive Symptoms, Antidepressant Use, and Brain Volumes on MRI in a Population-Based Cohort of Old Persons Without Dementia; Association of Vascular Factors and Amnestic Mild Cognitive Impairment: A Comprehensive Approach.
The Default Mode Network may be the Key Substrate of Depressive Symptom-Related Cognitive ChangesNeuropsychiatric Symptoms and Functional Connectivity in Mild Cognitive Impairment; Corpus Callosum Structure is Topographically Correlated with the Early Course of Cognition and Depression in Alzheimer's Disease; Regional Coherence Changes in Alzheimer's Disease Patients with Depressive Symptoms: A Resting-State Functional MRI Study; Brain Structure and Function Related to Depression in Alzheimer's Disease: Contributions from Neuroimaging Research; Section 6. Genetics.
Summary: Advances in healthcare have led to an extended life expectancy throughout the developed world, but cognitive impairment in later life, and Alzheimer's disease (AD) in particular, remains one of the intractable problems which can blight quality of life as we age. Depression in Alzheimer's disease is an additional factor which has a significant impact on disability, disease progression, and caregiver burden. This book, volume 4 of the Advances in Alzheimer's Disease book series which is published in coordination with the Journal of Alzheimer's Disease, presents papers which reflect the progress in recent years of research into depression in AD. This research has focused on several areas, including the improvement of diagnostic criteria and outcome measures for depression and depressive symptoms in AD, genetic and imaging studies to elucidate the neurobiological mechanisms, and clinical trials of antidepressants. The book is divided into sections on phenomenology, epidemiology, neuropsychology, neurobiology and neuropathology, neuroimaging, genetics, and treatment. Providing a stimulus to further research in this challenging area by engaging both basic and clinical researchers, this book will be of interest to all those whose work involves understanding and dealing with depression in those suffering from Alzheimer's disease.
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Electronic book Stenhouse Library (Kingston Hospital) Online Link to resource Available

Online resource; title from PDF title page (EBSCO, viewed August 27, 2015).

Includes bibliographical references and indexes.

Title Page; Preface; Contents; Section 1. Phenomenology; Phenomenology of Depression in Alzheimer's Disease; Apathy and Depression in Mild Alzheimer's Disease: A Cross-sectional Study using Diagnostic Criteria; Neuropsychiatric Symptoms in Alzheimer's Disease and Vascular Dementia; Section 2. Epidemiology; Depression in Alzheimer's Disease: Epidemiology, Mechanisms, and Management; Depression and Mild Cognitive Impairment in the General Population: Results of the Heinz Nixdorf Recall Study.

Late-Life Depression as a Risk Factor for Mild Cognitive Impairment or Alzheimer's Disease in 30 US Alzheimer's Disease CentersLatent Classes of Neuropsychiatric Symptoms in NACC Controls and Conversion to Mild Cognitive Impairment or Dementia; Section 3. Neuropsychology; Neuropsychological Functioning in the Acute and Remitted States of Late-Life Depression; Differential Cognitive Deterioration in Dementia: A Two Year Longitudinal Study; Coupled Cognitive and Functional Change in Alzheimer's Disease and the Infl uence of Depressive Symptoms.

Cognition, Gender, and Functional Abilities in Alzheimer's Disease: How are They Related?Gender-Specifi Differences in Cognitive Profiles of Patients with Alzheimer's Disease: Results of the Prospective Dementia Registry Austria (PRODEM-Austria); Section 4. Neurobiology and Neuropathology; Depression and Alzheimer's Disease: Is Stress the Initiating Factor in a Common Neuropathological Cascade?; The Role of Indoleamine 2,3-Dioxygenase in a Mouse Model of Neuroinfl ammation-Induced Depression; Depression and Alzheimer's Disease: Novel Postmortem Brain Studies Reveal a Possible Common Mechanism.

Neuropathology of Depression in Alzheimer's Disease: Current Knowledge and the Potential for New TreatmentsSection 5. Neuroimaging; Depressive Symptoms and Biomarkers of Alzheimer's Disease in Cognitively Normal Older Adults; Hippocampal Volume in Older Adults at Risk of Cognitive Decline: The Role of Sleep, Vascular Risk, and Depression; Depressive Symptoms, Antidepressant Use, and Brain Volumes on MRI in a Population-Based Cohort of Old Persons Without Dementia; Association of Vascular Factors and Amnestic Mild Cognitive Impairment: A Comprehensive Approach.

The Default Mode Network may be the Key Substrate of Depressive Symptom-Related Cognitive ChangesNeuropsychiatric Symptoms and Functional Connectivity in Mild Cognitive Impairment; Corpus Callosum Structure is Topographically Correlated with the Early Course of Cognition and Depression in Alzheimer's Disease; Regional Coherence Changes in Alzheimer's Disease Patients with Depressive Symptoms: A Resting-State Functional MRI Study; Brain Structure and Function Related to Depression in Alzheimer's Disease: Contributions from Neuroimaging Research; Section 6. Genetics.

Advances in healthcare have led to an extended life expectancy throughout the developed world, but cognitive impairment in later life, and Alzheimer's disease (AD) in particular, remains one of the intractable problems which can blight quality of life as we age. Depression in Alzheimer's disease is an additional factor which has a significant impact on disability, disease progression, and caregiver burden. This book, volume 4 of the Advances in Alzheimer's Disease book series which is published in coordination with the Journal of Alzheimer's Disease, presents papers which reflect the progress in recent years of research into depression in AD. This research has focused on several areas, including the improvement of diagnostic criteria and outcome measures for depression and depressive symptoms in AD, genetic and imaging studies to elucidate the neurobiological mechanisms, and clinical trials of antidepressants. The book is divided into sections on phenomenology, epidemiology, neuropsychology, neurobiology and neuropathology, neuroimaging, genetics, and treatment. Providing a stimulus to further research in this challenging area by engaging both basic and clinical researchers, this book will be of interest to all those whose work involves understanding and dealing with depression in those suffering from Alzheimer's disease.

English.

WorldCat record variable field(s) change: 650

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