Thrombotic thrombocytopenic purpura / [E-Book]

By:

Scully, Marie A [author.]

Contributor(s):

9783318070552 (PDF ebook) :

Subject(s):

Thrombotic thrombocytopenic purpura -- Popular works

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Summary: Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood coagulation system. In most cases, a lack of the ADAMTS13 enzyme leads to an accumulation of ultra-large von Willebrand factor molecules in the plasma which, in turn, initiate the formation of microscopic thromboses in small blood vessels. TTP is a medical emergency. Timely diagnosis and urgent and effective management are vital - mortality in those untreated is in the region of 90%. The understanding of TTP pathogenesis has increased markedly in recent decades. It is now known that TTP is acquired (immunemediated) or congenital, and that the most common type - the acquired form - predominantly affects women in their 40s.

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Item type	Home library	URL	Status
Electronic book	BEH-MHT Library Service Online	Link to resource	Available
Electronic book	CEME Library (NELFT) Online	Link to resource	Available
Electronic book	Croydon Health Services Library Online	Link to resource	Available
Electronic book	David Adams Library (Royal Marsden) Online	Link to resource	Available
Electronic book	Ferriman information and Library Service (North Middlesex) Online	Link to resource	Available
Electronic book	Hillingdon Hospitals Library Services (Hillingdon Hospitals NHS Foundation) Online	Link to resource	Available
Electronic book	Hirson Library (St Helier) Online	Link to resource	Available
Electronic book	Newcomb Library at Homerton Healthcare Online	Link to resource	Available
Electronic book	Newham Library (Barts Health) Online	Link to resource	Available
Electronic book	Oxleas NHS Foundation Trust Knowledge and Library Service Online	Link to resource	Available
Electronic book	PRUH Education Centre Library Online	Link to resource	Available
Electronic book	QEH Library (Lewisham and Greenwich) Online	Link to resource	Available
Electronic book	Queen's Hospital Jackie Blanks Library Online	Link to resource	Available
Electronic book	Royal London Library (Barts Health) Online	Link to resource	Available
Electronic book	Sally Howell Library (Epsom) Online	Link to resource	Available
Electronic book	South London and Maudsley Trust Library Online	Link to resource	Available
Electronic book	St Bartholomew's Library (Barts Health) Online	Link to resource	Available
Electronic book	St Charles Library Hub (Central and North West London NHS Foundation Trust) Online	Link to resource	Available
Electronic book	Stenhouse Library (Kingston Hospital) Online	Link to resource	Available
Electronic book	Thorpe Coombe Library Online	Link to resource	Available
Electronic book	UHL Library (Lewisham and Greenwich) Online	Link to resource	Available
Electronic book	Whipps Cross Library (Barts Health) Online	Link to resource	Available
Electronic book	Whittington Health Library Online	Link to resource	Available

Also issued in print: 2022.

Includes bibliographical references and index.

Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood coagulation system. In most cases, a lack of the ADAMTS13 enzyme leads to an accumulation of ultra-large von Willebrand factor molecules in the plasma which, in turn, initiate the formation of microscopic thromboses in small blood vessels. TTP is a medical emergency. Timely diagnosis and urgent and effective management are vital - mortality in those untreated is in the region of 90%. The understanding of TTP pathogenesis has increased markedly in recent decades. It is now known that TTP is acquired (immunemediated) or congenital, and that the most common type - the acquired form - predominantly affects women in their 40s.

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