Image-Guided High-Precision Radiotherapy [E-Book]

PART I) TARGET VOLUME DEFINITION -- Chapter 1) Use of [18F] FDG-PET for target volume definition in radiotherapy -- Chapter 2) Specific PET tracers for solid tumors and for definition of the biological target volume -- Chapter 3) Use of anatomical and functional MRI in radiation treatment planning-. PART II) IMAGE-GUIDED RT TECHNIQUES -- Chapter 4) In-room systems for patient positioning and motion control -- Chapter 5) IMRT/VMAT, SABR -- Chapter 6) Magnetic resonance-guided adaptive radiotherapy - technical concepts -- Chapter 7) MR-integrated linear accelerators - first clinical results -- Chapter 8) Image-guided adaptive brachytherapy -- Chapter 9) Ultrasonography in image-guided radiotherapy - current status and future challenges -- Chapter 10) Means for target volume delineation and stabilisation: fiducial markers, balloons, and others -- Chapter 11) Artificial intelligence in radiation oncology: a rapidly evolving picture -- PART III) OUTCOME EVALUATION -- Chapter 12) Multimodality imaging for prediction of tumour control following radiotherapy -- Chapter 13) Modelling for radiation treatment outcome.

This book equips readers with detailed knowledge on the current status of image-guided radiotherapy with photons and particles and highlights issues that need to be addressed in order to further improve treatment outcomes. The opening chapters cover clinical and technical aspects of target volume definition using anatomic (computed tomography and magnetic resonance imaging; MRI) as well as functional (MRI and positron emission tomography) imaging. Up-to-date information is then provided on the full range of image-guided high-precision radiotherapy techniques, including IMRT/VMAT, stereotactic body radiation therapy, MR-guided linear accelerators, MR-guided brachytherapy, and particle therapy. The role of ultrasonography in image-guided radiotherapy is discussed, as are the available means for target volume demarcation and stabilization and adaptive radiation therapy. Finally, outcome evaluation is explored in depth, with a particular focus on the role of multimodality imaging in predicting tumor control and normal tissue toxicity. The authors are experts in different specialties and the book will be of high value for radiation oncologists, medical physicists, radiologists, nuclear medicine physicians, and radiation technicians.