Maternal and neonatal outcomes of spontaneously conceived pregnancies in mothers over 45 years: a review of the literature.

By:

Wong-Taylor, L.A

Contributor(s):

Publication details: 2012ISSN:

09320067

Uniform titles:

Archives of Gynecology and Obstetrics

Online resources:

Summary: <div style="line-height: 17.999801635742188px;"><h4 style="font-size: 1em; font-family: arial, helvetica, clean, sans-serif; margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left;">PURPOSE:</h4>There is little published data on pregnancy outcomes in women who had conceived spontaneously after age 45 years. The aim of thisreview is to provide accurate information on the risks and probable outcomes of spontaneously conceived pregnancies in women over the age of 45years, which will enable clinicians to counsel such women appropriately, carry out adequate risk assessment, and ensure better care for pregnanciesin this population.<h4 style="margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left;">DESIGN:</h4>A literature search was performed using EmBase and PubMed for English language articles published between 1970 and 2011, with extractable data on mothers aged ≥45 at the time of delivery and with ≥95% spontaneous conception in the study population.<h4 style="margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left;">RESULTS:</h4>Six such studies with a total pooled number of 505 women were identified. Overall, there is increased maternal morbidity and rates of caesarean section, as well as higher incidence of premature births and admission to special care baby unit. Contrary to popular belief, career is not always an important factor in delaying childbearing, especially in developing countries. Other factors may include cultural acceptance of large families and lack of contraception, although more research may be carried out in order to explain these hypotheses.<h4 style="margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left;">CONCLUSION:</h4>Pooled retrospective data suggest that women who conceived spontaneously after the age of 45 years have increased maternalmorbidity and rates of caesarean section, as well as higher incidence of premature births and admission to special care baby unit.</div>

Holdings
Item type	Home library	Collection	Class number	Status	Date due	Barcode
UNKNOWN	Ferriman information and Library Service (North Middlesex) Online	Staff publications for NMDX		Available

NMUH Staff Publications

285

<div style="line-height: 17.999801635742188px;"><h4 style="font-size: 1em; font-family: arial, helvetica, clean, sans-serif; margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left;">PURPOSE:</h4>There is little published data on&nbsp;pregnancy&nbsp;outcomes&nbsp;in women who had&nbsp;conceived&nbsp;spontaneously&nbsp;after age&nbsp;45&nbsp;years. The aim of thisreview&nbsp;is to provide accurate information on the risks and probable&nbsp;outcomes&nbsp;of&nbsp;spontaneously&nbsp;conceived&nbsp;pregnancies&nbsp;in women&nbsp;over&nbsp;the age of&nbsp;45years, which will enable clinicians to counsel such women appropriately, carry out adequate risk assessment, and ensure better care for&nbsp;pregnanciesin this population.<h4 style="margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left;">DESIGN:</h4>A&nbsp;literature&nbsp;search was performed using EmBase and PubMed for English language articles published between 1970 and 2011, with extractable data on&nbsp;mothers&nbsp;aged ≥45&nbsp;at the time of delivery and with ≥95% spontaneous conception in the study population.<h4 style="margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left;">RESULTS:</h4>Six such studies with a total pooled number of 505 women were identified. Overall, there is increased&nbsp;maternal&nbsp;morbidity and rates of caesarean section, as well as higher incidence of premature births and admission to special care baby unit. Contrary to popular belief, career is not always an important factor in delaying childbearing, especially in developing countries. Other factors may include cultural acceptance of large families and lack of contraception, although more research may be carried out in order to explain these hypotheses.<h4 style="margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left;">CONCLUSION:</h4>Pooled retrospective data suggest that women who&nbsp;conceived&nbsp;spontaneously&nbsp;after the age of&nbsp;45&nbsp;years&nbsp;have increased&nbsp;maternalmorbidity and rates of caesarean section, as well as higher incidence of premature births and admission to special care baby unit.</div>

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