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001 978-981-16-9186-7
003 DE-He213
005 20240729133642.0
007 cr nn 008mamaa
008 220607s2022 si | s |||| 0|eng d
020 _a9789811691867
_9978-981-16-9186-7
024 7 _a10.1007/978-981-16-9186-7
_2doi
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
072 7 _aMJCL
_2thema
245 1 0 _aRole of MicroRNAs in Cancers
250 _a1st ed. 2022.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2022.
300 _aXIV, 176 p. 1 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aChapter 1. Introduction to microRNAs and cancers -- Chapter 2. microRNAs and cancer signaling pathways -- Chapter 3. Role of microRNAs in cell growth proliferation and tumorigenesis -- Chapter 4. Impact of microRNAs in cell adhesion and tumor angiogenesis -- Chapter 5. Modulation of oxidative stress by microRNAs in cancers -- Chapter 6. microRNAs targeting tumor microenvironment and immune modulation -- Chapter 7. Circulating miRNA in prognosis, diagnosis and their role in controlling the fate of cancer stem cells -- Chapter 8. The role of miRNAs in the regulation of drug resistance among different cancers -- Chapter 9. The mechanisms of miRNA deregulation in cancer outbreak -- Chapter 10. Bioinformatic profiling of miRNAs in Cancers.
520 _aThis book discusses the potential roles of miRNA as a crucial regulator in cancer biology. It examines the regulation of drug resistance by miRNAs in cancers and the mechanism of their deregulated expression. The book discusses the role and molecular mechanism of miRNA in regulating cellular proliferation and cell cycle. It analyses circulating miRNAs as biomarkers for cancer diagnosis and prognosis. It also analyzes the role of miRNA as a modulator of the development and function of tumor-associated immune cells. It explores the cross-talk between miRNA and reactive oxygen species (ROS) in pathogenesis, cancer therapeutic tolerance, and resistance. It provides insights into the role of miRNA in cancer angiogenesis, metastasis and describes strategies and associated challenges of miRNA-based therapies.
650 0 _aCancer
_xTreatment.
650 0 _aRNA interference.
650 0 _aImmunology.
650 0 _aBiochemical markers.
650 1 4 _aCancer Therapy.
650 2 4 _aRNA Interference.
650 2 4 _aImmunology.
650 2 4 _aBiomarkers.
700 1 _aPrasad, DKV.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aSantosh Sushma, Pinninti.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
856 _u#gotoholdings
_yAccess resource
912 _aZDB-2-SBL
912 _aZDB-2-SXB
245 _h[E-Book]
999 _c100643
_d100643