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020 _a9783030866846
_9978-3-030-86684-6
024 7 _a10.1007/978-3-030-86684-6
_2doi
072 7 _aMJCM
_2bicssc
072 7 _aMED044000
_2bisacsh
072 7 _aMJCM
_2thema
245 1 0 _aEssential Aspects of Immunometabolism in Health and Disease
250 _a1st ed. 2022.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2022.
300 _aXII, 278 p. 38 illus., 37 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aOverview of Immune response -- Metabolic Pathway: from biochemistry to bench -- Mitochondrial biogenesis and dynamics in healthy and diseases -- Epigenetic regulation of metabolic pathways -- Metabolic pathways and cells signaling -- Metabolic profile of innate and adaptive immune cells -- Metabolic sensors and immunopathology -- Obesity, metabolic syndrome and inflammation.
520 _aImmunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different immune cells types and in different conditions, can shed light into the molecular mechanisms of disease and help develop new drugs and therapeutic strategies to treat immune diseases. The edited volume Essentials aspects of Immunometabolism will give the readers a broad view on how metabolic pathways can influence many types of immune cells during activation, differentiation and function, in health and disease. Of note, the structure of the book was created thinking not only on the experienced immunologist but also on undergraduate and graduate students, physicians, and all members of the scientific community interested in this exciting field of research.
650 0 _aImmunology.
650 0 _aHuman physiology.
650 0 _aPathology.
650 1 4 _aImmunology.
650 2 4 _aHuman Physiology.
650 2 4 _aPathology.
700 1 _aCamara, Niels Olsen Saraiva.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aAlves-Filho, Jose C.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aMoraes-Vieira, Pedro Manoel Mendes de.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aAndrade-Oliveira, Vinicius.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
856 _u#gotoholdings
_yAccess resource
912 _aZDB-2-SBL
912 _aZDB-2-SXB
245 _h[E-Book]
999 _c100800
_d100800