000			04013nam a22004215i 4500
001			978-3-030-91623-7
003			DE-He213
005			20240729133828.0
007			cr nn 008mamaa
008			220314s2022 sz | s |||| 0|eng d
020			_a9783030916237 _9978-3-030-91623-7
024	7		_a10.1007/978-3-030-91623-7 _2doi
072		7	_aMFG _2bicssc
072		7	_aSCI036000 _2bisacsh
072		7	_aMFG _2thema
245	1	0	_aPhosphate Metabolism _b : From Physiology to Toxicity /
250			_a1st ed. 2022.
264		1	_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2022.
300			_aVIII, 163 p. 1 illus. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aAdvances in Experimental Medicine and Biology, _x2214-8019 ; _v1362
505	0		_aPreface -- Chapter 1. Phosphate Metabolism: from Physiology to Toxicity (Mohammed S. Razzaque) -- Chapter 2. Phosphate Burden and Inflammation (Sarah Erem , Satoko Osuka and Mohammed S. Razzaque) -- Chapter 3. Extracellular Phosphate, Inflammation and Cytotoxicity (Toshimi Michigami, Miwa Yamazaki, Mohammed S. Razzaque) -- Chapter 4. Phosphate-sensing (Yuichi Takashi and Seiji Fukumoto) -- Chapter 5. Vitamin D and phosphate interactions in health and disease (Nuraly S. Akimbekov, Ilya Digel, Dinara K. Sherelkhan, Mohammed S. Razzaque) -- Chapter 6. Fibroblast growth factor 23 as regulator of vitamin D metabolism (Shinya Nakatani; Ayumi Nakatani, Katsuhito Mori, Masanori Emoto; Masaaki Inaba; and Mohammed S. Razzaque) -- Chapter 7. Phosphate and Cellular Senescence (Ming Chang Hu and Orson W. Moe) -- Chapter 8. Phosphate toxicity and epithelial to mesenchymal transition (EMT) (Eric Lewis, Faith Seltun, Mohammed S. Razzaque, Ping He) -- Chapter 9. Phosphate & endothelial function: How sensing ofelevated inorganic phosphate concentration generates signals in endothelial cells (Nima Abbasian, Alan Bevington and Dylan Burger) -- Chapter 10. Common dietary sources of natural and artificial phosphate in food (Ken-ichi Miyamoto, Joanna Oh, Mohammed S. Razzaque) -- Chapter 11. Phosphate is a Cardiovascular Toxin (Maren Leifheit-Nestler, Isabel Vogt, Dieter Haffner and Beatrice Richter) -- Chapter 12. Coordination of Phosphate and Magnesium Metabolism in Bacteria (Roberto E. Bruna, Christopher G. Kendra and Mauricio H. Pontes) -- Index.
520			_aThis contributed volume discusses the most important physiological aspects of phosphate metabolism, and how its pathological dysregulation can induce organ damage, which includes but is not limited to blood vessels, kidney, bone and tumor. The editor has selected a varied group of world renowned experts to provide a basic understanding of normal phosphate regulation, to then move on to explain the complex molecular mechanisms of abnormal phosphate regulation, also shedding some light on the downstream clinical consequences owing to phosphate toxicity. Each chapter clearly presents the biochemically important problems related to phosphate dysregulation with the necessary illustrations. Readers will be able to use the proposed book as a quick reference for updated information on phosphate metabolism, ranging from cellular system to physiology, from pathology to toxicity, also including the associated clinical consequences, without much prior acquaintance with the field.
650		0	_aHuman physiology.
650	1	4	_aHuman Physiology.
700	1		_aRazzaque, Mohammed S. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service)
830		0	_aAdvances in Experimental Medicine and Biology, _x2214-8019 ; _v1362
856			_u#gotoholdings _yAccess resource
912			_aZDB-2-SBL
912			_aZDB-2-SXB
245			_h[E-Book]
999			_c100830 _d100830