000 04127nam a22005295i 4500
001 978-981-15-9411-3
003 DE-He213
005 20240821192923.0
007 cr nn 008mamaa
008 220131s2022 si | s |||| 0|eng d
020 _a9789811594113
_9978-981-15-9411-3
024 7 _a10.1007/978-981-15-9411-3
_2doi
072 7 _aMBGR
_2bicssc
072 7 _aMED062000
_2bisacsh
072 7 _aMBGR
_2thema
245 1 0 _aHandbook of Oxidative Stress in Cancer: Mechanistic Aspects
250 _a1st ed. 2022.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2022.
300 _a388 illus., 324 illus. in color. eReference.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aInvolvement of ROS in thyroid cancer -- Skin cancer induced by pollution-medicated ROS -- Roles of β-Glucans in Oxidative Stress and Cancer -- Oxidative stress in glioma and its microenvironment -- Reactive oxygen species and their contribution to carcinogenesis -- Oral cancer and oxidative stress -- Oxidative stress in genitourinary cancer -- Oxidative stress in oral cancer -- Oxidative stress and glyoxalase pathway in cancer -- ROS and EMT in multistep carcinogenesis -- Functional regulation between matrix metalloproteases and cell junction proteins in gastric cancer -- Association of oxidative stress and mitochondrial dysfunction to gynaecological malignancies -- Impact of Caenorhabdits elegans in cancdeer drug resistance and development -- Pharmacology of natural products specifically plant based mitigating cisplatin-induced cardiotoxicity and attenuating oxidative stress, inflammation and associated signalling pathways -- Scafold based selective ROS generation as viable therapeutic strategies.
520 _aThis comprehensive, up-to-date reference work compiles the scientific research on the relationship between various forms of cancer and reactive oxygen species (ROS). It is well known that ROS play a key role in the various steps leading to malignancy, this includes increase in DNA mutation rates. The book brings together exciting reviews, written by leading experts all over the world. The book is divided into four broad sections. Each section describes the role of oxidative stress and underlying mechanisms and pathways, at various stages of cancer, including its role in carcinogenesis, cancer progression and metastasis. Further, the book describes how the reactive oxygen species (ROS) modulate gene expression and signal transduction pathways in cancer. The book discusses the ways to interfere with the cancer progression, and design of anti-cancer drugs. The book provides an integrated approach for better understanding of the development phases of oxidative stress-induced cancers, and mainly the current perspectives about mechanistic aspects of cancer initiation, progression and metastasis. It is a highly resourceful book and would be extremely important to clinicians, students and researchers in the field of cancer genetics, therapeutics and oncology.
650 0 _aMedicine
_xResearch.
650 0 _aBiology
_xResearch.
650 0 _aCytology.
650 0 _aMedical genetics.
650 0 _aHuman physiology.
650 0 _aBiotechnology.
_95393
650 1 4 _aBiomedical Research.
650 2 4 _aCell Biology.
650 2 4 _aMedical Genetics.
650 2 4 _aHuman Physiology.
650 2 4 _aBiotechnology.
_95393
700 1 _aChakraborti, Sajal.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aRay, Bimal K.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aRoychoudhury, Susanta.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
856 _u#gotoholdings
_yAccess resource
912 _aZDB-2-SBL
912 _aZDB-2-SXRB
245 _h[E-Book]
999 _c101018
_d101018