000			02966nam a22005175i 4500
001			978-981-19-5595-2
003			DE-He213
005			20240729134156.0
007			cr nn 008mamaa
008			221019s2022 si | s |||| 0|eng d
020			_a9789811955952 _9978-981-19-5595-2
024	7		_a10.1007/978-981-19-5595-2 _2doi
072		7	_aMJCM _2bicssc
072		7	_aMED044000 _2bisacsh
072		7	_aMJCM _2thema
100	1		_aGanguly, Dipyaman. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut
245	1	0	_aPlasmacytoid Dendritic Cells
250			_a1st ed. 2022.
264		1	_aSingapore : _bSpringer Nature Singapore : _bImprint: Springer, _c2022.
300			_aIX, 163 p. 20 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aChapter 1_Dendritic cells and the basic principles of immune functions -- Chapter 2_Discovery of a new dendritic cell -- Chapter 3_Hematopoietic origins of plasmacytoid dendritic cells -- Chapter 4_Molecular regulation of plasmacytoid dendritic cell identity -- Chapter 5_Type I interferon production by plasmacytoid dendritic cells -- Chapter 6_Tolerogenic functions of plasmacytoid dendritic cells -- Chapter 7_Plasmacytoid dendritic cells and infections -- Chapter 8_Plasmacytoid dendritic cells in autoimmunity and allergy -- Chapter 9_Plasmacytoid dendritic cells and metabolic disorders -- Chapter 10_ Plasmacytoid dendritic cells and cancer -- Chapter 11_Therapeutic targeting of plasmacytoid dendritic cells -- Chapter 12_Experimental methodology for plasmacytoid dendritic cells.
520			_aThis book provides a systematic review of the development, function, and patho-physiologic role of plasmacytoid dendritic cells (pDCs) in humans. The chapters of the book discuss the origin and discovery, hematopoietic development as well as molecular regulation of pDCs in the context of immune activation as well as immune tolerance. It also discusses the role of pDCs in human diseases, including infections, autoimmune/inflammatory diseases, cancers and metabolic disorders, and opportunities for pDC‐targeting therapies in these varied clinical contexts. .
650		0	_aImmunology.
650		0	_aCancer.
650		0	_aNatural immunity.
650		0	_aImmunologic diseases. _96573
650		0	_aAutoimmunity.
650		0	_aInflammation. _96609
650	1	4	_aImmunology.
650	2	4	_aCancers.
650	2	4	_aInnate Immunity.
650	2	4	_aImmunological Disorders.
650	2	4	_aAutoimmunity.
650	2	4	_aInflammation. _96609
710	2		_aSpringerLink (Online service)
856			_u#gotoholdings _yAccess resource
912			_aZDB-2-SBL
912			_aZDB-2-SXB
245			_h[E-Book]
999			_c101191 _d101191