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001 978-3-030-81261-4
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020 _a9783030812614
_9978-3-030-81261-4
024 7 _a10.1007/978-3-030-81261-4
_2doi
072 7 _aMMN
_2bicssc
072 7 _aMED080000
_2bisacsh
072 7 _aMKR
_2thema
245 1 0 _aNuclear Medicine and Immunology
250 _a1st ed. 2022.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2022.
300 _aXIV, 534 p. 112 illus., 101 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _a1. Molecular Imaging in Inflammatory and Autoimmune Disorders -- 2. Gallium Imaging of Infection and Inflammation -- 3. 111Indium-Labeled Leukocyte Imaging of Infection and Inflammation -- 4. 99mTc-HMPAO-Labeled-Leukocyte Imaging of Infection and Inflammation -- 5. FDG-PET Imaging of Infection and Inflammation -- 6. Imaging Procedures with Radiolabeled Monoclonal Antibodies -- 7. Dosimetric Principles of Targeted Radiotherapy -- 8. Radioimmunotherapy (RIT) -- 9. Peptide Receptor Radionuclide Therapy (PRRT) -- 10. Tumor Architecture and Targeted Delivery -- 11. Antibodies and Novel Constructs for Tumor Targeting -- 12. Pretargeted Radioimmunotherapy of Cancer -- 13. Radioimmunotherapy of Lymphoma -- 14. Radioimmunotherapy in Brain Tumors -- 15. Radioimmunotherapy of Pancreatic Adenocarcinoma -- 16. Radioimmunotherapy of Renal Cell Carcinoma -- 17. Radioimmunotherapy of Prostate Carcinoma -- 18. Radioimmunotherapy of Ovarian Cancer -- 19. Targeted Radiotherapy in the Treatment of Osteosarcoma -- 20. Targeted Radiotherapy of Neuroblastoma -- 21. Targeted Radiotherapy of Squamous Cell Carcinoma of the Head and Neck -- 22. Moving Forward: Expected Opportunities for the Development of New Therapeutic Agents -- 23. Translation of Radiopharmaceuticals from Bench to Bedside.
520 _aThis book explores the close connection between immunology and nuclear medicine, which has led to radioimmunoimaging and radioimmunotherapy (RIT). Molecular imaging with positron emission tomography (PET) and single-photon emission computed tomography (SPECT) is increasingly being used to diagnose, characterize, and monitor disease activity in the context of inflammatory disorders of known and unknown etiology, such as sarcoidosis, atherosclerosis, vasculitis, inflammatory bowel disease, rheumatoid arthritis, and degenerative joint disease. The first chapters discuss the various radiopharmaceutical agents and radiolabeled preparations that have been employed in inflammation imaging. Of these, FDG-PET imaging has been shown to have the great value in the detection of inflammation and has become the centerpiece of several initiatives over the last several years. This very powerful technique will play an increasingly important role in the management of patients with inflammatory conditions in the future. The book also explores the growing role of nuclear medicine and molecular imaging in the diagnosis and treatment of cancer. The rapid pace of change has been fueled by advances in our understanding of tumor biology, on the one hand, and the development of specifically targeted medical therapies, diagnostic agents, and radiotherapies, on the other. Written by leading international experts in the field, this book is an invaluable tool for nuclear medicine physicians, radiologists, oncologists, and immunologists.
650 0 _aNuclear medicine.
650 0 _aOncology.
_913364
650 0 _aRadiology.
650 0 _aImmunology.
650 1 4 _aNuclear Medicine.
650 2 4 _aOncology.
_913364
650 2 4 _aRadiology.
650 2 4 _aImmunology.
700 1 _aHarsini, Sara.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aAlavi, Abass.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aRezaei, Nima.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
856 _u#gotoholdings
_yAccess resource
912 _aZDB-2-SME
912 _aZDB-2-SXM
245 _h[E-Book]
999 _c101692
_d101692