000 | 03725nam a22004335i 4500 | ||
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001 | 978-3-030-39044-0 | ||
003 | DE-He213 | ||
005 | 20240729135127.0 | ||
007 | cr nn 008mamaa | ||
008 | 230420s2023 sz | s |||| 0|eng d | ||
020 |
_a9783030390440 _9978-3-030-39044-0 |
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024 | 7 |
_a10.1007/978-3-030-39044-0 _2doi |
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072 | 7 |
_aMJ _2bicssc |
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072 | 7 |
_aMED045000 _2bisacsh |
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072 | 7 |
_aMJ _2thema |
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245 | 1 | 0 |
_aEnvironmental Endocrinology and Endocrine Disruptors _b : Endocrine and Endocrine-targeted Actions and Related Human Diseases / |
250 | _a1st ed. 2023. | ||
264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2023. |
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300 |
_a40 illus., 2 illus. in color. eReference. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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490 | 1 |
_aEndocrinology, _x2510-1935 |
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505 | 0 | _aEnvironmental endocrinology: basic concepts -- Environmental impact on the hypothalamus-pituitary axis -- Environmental impact on the hypothalamus-pituitary-thyroid axis -- Environmental impact on the hypothalamus-pituitary-adrenal axis -- Environmental impact on the hypothalamus-pituitary-ovary axis -- Environmental impact on female fertility and pregnancy -- The role of the environment in female reproductive disorders -- Environmental impact on the hypothalamus-pituitary-testis axis -- Environmental impact on semen quality and male fertility -- The role of the environment in testicular dysgenesis syndrome -- Environmental impact on sexual response -- Environmental impact on bone health -- Environmental impact on the immune system -- Environmental impact on metabolism -- The role of the environment in neuroendocrine tumors -- The role of the environment in endocrine cancers -- The role of the environmentin hormone-related cancers. | |
520 | _aThis book describes how exposure to various classes of endocrine disruptors, as well as other environmental chemicals targeting the endocrine system by alternative non-endocrine mechanisms, impact on endocrinological and endocrinological-related diseases. It includes comprehensive reviews of all aspects of environmental endocrinology, ranging from sources and patterns of exposure and identification of endocrine targets to direct endocrine disruptive mechanisms and indirect actions on the endocrine system, the latter including endocrine cell-directed cytotoxicity, oxidative damage, and genetic and epigenetic aberrations resulting in endocrine damage. It also examines the causal pathways and offers an extensive overview of downstream endocrinological and endocrinological-related disorders. In addition, several chapters focus on transgenerational actions, which are a topic of particular interest. Lastly, evidence from preclinical and clinical studies provides the basis for an in-depth, critical discussion of each topic. The book is part of the SpringerReference program, which provides access to 'living editions' that are constantly updated using a dynamic peer-review publishing process. | ||
650 | 0 |
_aInternal medicine. _96654 |
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650 | 1 | 4 |
_aInternal Medicine. _96654 |
700 | 1 |
_aPivonello, Rosario. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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700 | 1 |
_aDiamanti-Kandarakis, Evanthia. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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710 | 2 | _aSpringerLink (Online service) | |
830 | 0 |
_aEndocrinology, _x2510-1935 |
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856 |
_u#gotoholdings _yAccess resource |
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912 | _aZDB-2-SME | ||
912 | _aZDB-2-SXRM | ||
245 | _h[E-Book] | ||
999 |
_c102398 _d102398 |