000 03725nam a22004335i 4500
001 978-3-030-39044-0
003 DE-He213
005 20240729135127.0
007 cr nn 008mamaa
008 230420s2023 sz | s |||| 0|eng d
020 _a9783030390440
_9978-3-030-39044-0
024 7 _a10.1007/978-3-030-39044-0
_2doi
072 7 _aMJ
_2bicssc
072 7 _aMED045000
_2bisacsh
072 7 _aMJ
_2thema
245 1 0 _aEnvironmental Endocrinology and Endocrine Disruptors
_b : Endocrine and Endocrine-targeted Actions and Related Human Diseases /
250 _a1st ed. 2023.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2023.
300 _a40 illus., 2 illus. in color. eReference.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aEndocrinology,
_x2510-1935
505 0 _aEnvironmental endocrinology: basic concepts -- Environmental impact on the hypothalamus-pituitary axis -- Environmental impact on the hypothalamus-pituitary-thyroid axis -- Environmental impact on the hypothalamus-pituitary-adrenal axis -- Environmental impact on the hypothalamus-pituitary-ovary axis -- Environmental impact on female fertility and pregnancy -- The role of the environment in female reproductive disorders -- Environmental impact on the hypothalamus-pituitary-testis axis -- Environmental impact on semen quality and male fertility -- The role of the environment in testicular dysgenesis syndrome -- Environmental impact on sexual response -- Environmental impact on bone health -- Environmental impact on the immune system -- Environmental impact on metabolism -- The role of the environment in neuroendocrine tumors -- The role of the environment in endocrine cancers -- The role of the environmentin hormone-related cancers.
520 _aThis book describes how exposure to various classes of endocrine disruptors, as well as other environmental chemicals targeting the endocrine system by alternative non-endocrine mechanisms, impact on endocrinological and endocrinological-related diseases. It includes comprehensive reviews of all aspects of environmental endocrinology, ranging from sources and patterns of exposure and identification of endocrine targets to direct endocrine disruptive mechanisms and indirect actions on the endocrine system, the latter including endocrine cell-directed cytotoxicity, oxidative damage, and genetic and epigenetic aberrations resulting in endocrine damage. It also examines the causal pathways and offers an extensive overview of downstream endocrinological and endocrinological-related disorders. In addition, several chapters focus on transgenerational actions, which are a topic of particular interest. Lastly, evidence from preclinical and clinical studies provides the basis for an in-depth, critical discussion of each topic. The book is part of the SpringerReference program, which provides access to 'living editions' that are constantly updated using a dynamic peer-review publishing process.
650 0 _aInternal medicine.
_96654
650 1 4 _aInternal Medicine.
_96654
700 1 _aPivonello, Rosario.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aDiamanti-Kandarakis, Evanthia.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
830 0 _aEndocrinology,
_x2510-1935
856 _u#gotoholdings
_yAccess resource
912 _aZDB-2-SME
912 _aZDB-2-SXRM
245 _h[E-Book]
999 _c102398
_d102398