000 03312nam a22004455i 4500
001 978-981-19-4492-5
003 DE-He213
005 20240729135151.0
007 cr nn 008mamaa
008 230116s2023 si | s |||| 0|eng d
020 _a9789811944925
_9978-981-19-4492-5
024 7 _a10.1007/978-981-19-4492-5
_2doi
072 7 _aMNG
_2bicssc
072 7 _aMED031000
_2bisacsh
072 7 _aMNG
_2thema
245 1 0 _aMicrobiome in Gastrointestinal Cancer
250 _a1st ed. 2023.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2023.
300 _aVI, 302 p. 24 illus., 17 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aIntroduction -- Gut microbiome in health and diseases -- Microbiome in colorectal cancer -- Microbiome in gastric cancer -- Microbiome in liver cancer -- Virus, fungi and archaea in gastrointestinal cancer -- Microbial metabolomics in gastrointestinal cancer -- Diet and gut microbiome in gastrointestinal cancer -- Diet and gut microbiome in fatty liver and its associated liver cancer -- Host-microbiome interaction in gastrointestinal cancer -- Gut microbiome and immune responses in gastrointestinal cancer -- Animal models in the study of microbiome in gastrointestinal cancer -- High-throughput sequencing data analyses for microbiome profiling -- Gut microbiota modulation: probiotics and prebiotics in gastrointestinal cancer -- Roles of gut microbiota in efficacy of anticancer treatment of gastrointestinal cancer -- Targeting gut microbiota to treat gastrointestinal cancer.
520 _aThis book covers state-of-the-art topics covering evidences indicate that the gut microbiota can be harnessed for cancer prevention as well as to modulate the efficacy of chemotherapy and immunotherapy. This book includes: 1) characterization of the dysregulated microbiome in gastrointestinal cancers (Chapters 1-6); 2) the molecular mechanism of action of gut microbiota via microbial metabolites and direct interaction with host cancer or immune cells (Chapters 7-11); 3) key methodologies for studying the role of gut microbiota in cancers (Chapters 12-13); and 4) the potential application of gut microbes for the prevention and treatment of gastrointestinal cancers (Chapters 14-17). The contributors are international experts in molecular and cellular biology, microbiology, metabolomics, bioinformatics and physician scientists to provide in-depth reviews of this subject. This book provides a rich resource of information on this important topic for graduate students, basic researchers and physicians.
650 0 _aGastroenterology.
_96257
650 0 _aMedical microbiology.
650 0 _aOncology.
_913364
650 1 4 _aGastroenterology.
_96257
650 2 4 _aMedical Microbiology.
650 2 4 _aOncology.
_913364
700 1 _aYu, Jun.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
856 _u#gotoholdings
_yAccess resource
912 _aZDB-2-SME
912 _aZDB-2-SXM
245 _h[E-Book]
999 _c102455
_d102455