000 03785nam a22005415i 4500
001 978-3-031-17572-5
003 DE-He213
005 20240729135215.0
007 cr nn 008mamaa
008 230311s2023 sz | s |||| 0|eng d
020 _a9783031175725
_9978-3-031-17572-5
024 7 _a10.1007/978-3-031-17572-5
_2doi
072 7 _aMMKL
_2bicssc
072 7 _aMED015000
_2bisacsh
072 7 _aMKPL
_2thema
245 1 0 _aManagement of Dysregulated Immune Response in the Critically Ill
250 _a1st ed. 2023.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2023.
300 _aXXIII, 311 p. 33 illus., 32 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aLessons from the ICU, Under the Auspices of the European Society of Intensive Care Medicine,
_x2522-5936
505 0 _aForeword -- Preface -- Part I. The Host Immune Response -- Phenotypes -- The Dysregulated Host Response -- What is Cytokine Storm? -- Hemophagocytic Lymphohistiocytosis -- Extracorporeal Circulation Related Immune response -- Vasoplegic Shock -- Part II. Assessing Dysregulated Immune Response at the Bedside -- Pro- and anti-inflammatory biomarkers -- How to interpret procalcitonin? -- Assessment of the macro-, and microcirculation -- Part III. Dysregulated Immune Response and organ dysfunction -- Heart and circulation -- Brain -- Kidneys -- Liver -- Hemostasis -- The muscles -- Part IV. Modulating the immune response -- The Role of Steroids -- Why did Anti-Cytokine Therapies Fail in the Past? -- Extracorporeal cytokine removal.
520 _aThis book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new term introduced by the Sepsis-3 definitions in 2016. In contrast to systemic inflammatory response syndrome (SIRS) that has been used for nearly 30 years, this is a fundamentally new concept, which requires some sort of a paradigm shift in the way of thinking of critical care physicians. This change obviously requires time and after 5 years, time is ripe to summarize the knowledge in the form of a comprehensive book. The book is split in 4 sections. In the first one, the host immune response is explained in 11 chapters, followed by the next part, summarizing the possible tools for assessment at the bedside. The third and the fourth parts focus on the effects of dysregulated immune response on vital organ function and on the possible ways of immunomodulation. Written by internationally acclaimed experts of the field, the book is of value for all those intensivists and allied professionals working in ICUs.
650 0 _aCritical care medicine.
650 0 _aImmunology.
650 0 _aNephrology.
650 0 _aCardiology.
650 0 _aRespiratory organs
_xDiseases.
650 1 4 _aIntensive Care Medicine.
650 2 4 _aImmunology.
650 2 4 _aNephrology.
650 2 4 _aCardiology.
650 2 4 _aPneumology.
700 1 _aMolnar, Zsolt.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aOstermann, Marlies.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aShankar-Hari, Manu.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
830 0 _aLessons from the ICU, Under the Auspices of the European Society of Intensive Care Medicine,
_x2522-5936
856 _u#gotoholdings
_yAccess resource
912 _aZDB-2-SME
912 _aZDB-2-SXM
245 _h[E-Book]
999 _c102504
_d102504