000			03928nam a22005055i 4500
001			978-3-031-26945-5
003			DE-He213
005			20240729140150.0
007			cr nn 008mamaa
008			230716s2023 sz | s |||| 0|eng d
020			_a9783031269455 _9978-3-031-26945-5
024	7		_a10.1007/978-3-031-26945-5 _2doi
072		7	_aPSAN _2bicssc
072		7	_aSCI089000 _2bisacsh
072		7	_aPSAN _2thema
245	1	0	_aPurinergic Signaling in Neurodevelopment, Neuroinflammation and Neurodegeneration
250			_a1st ed. 2023.
264		1	_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2023.
300			_aX, 376 p. 34 illus., 3 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aThe Purinergic Signaling: Overview -- Adenosine A2A Receptor-containing Heteromers and Neuroprotection -- Purinergic Signaling in Brain Physiology -- Neurotrophic Actions of Adenosine and Guanosine: Implications for Neural Development and Regeneration? -- Purinergic Signaling in Neurogenesis and Neural Fate Determination: Current Knowledge and Future Challenges -- Purinergic Signaling in Autism Spectrum Disorder -- Purinergic Signaling in Depression -- Roles of Purinergic Receptors in Alzheimer's Disease -- Purinergic Signaling in Basal Ganglia Diseases: Parkinson's Disease -- A Step in the ALS Direction: Lessons from the Purinome -- Purinergic P2 Receptors in Epilepsy -- Purinergic Signaling in Neuroinflammation -- Purinergic Signaling in Brain Tumors -- Development of Purinergic Receptor Agonists and Antagonists -- Acupuncture for Counteracting P2X4 and P2X7 Receptor Involvement in Neuroinflammation.
520			_aThis volume explores the quickly evolving field of Purinergic signaling, and examines how receptors for ATP and other nucleotides, and receptors for adenosine, act in neuronal transmission, control of synaptic activity, proliferation, differentiation and cell death regulation in the CNS. This book focuses on the participation of purinergic receptors and ectonucleotidases, degrading ATP into adenosine, in embryonic and adult neurogenesis in vitro and in vivo as well as in synaptic transmission and pathophysiology. Further, the chapters discuss varying brain diseases, including Parkinson's, and Alzheimer's disease, autism, mood disorders and epilepsy, as well as brain tumors, in the context of purinergic signaling and its clinical aspects. The development of purinergic receptor agonists is also an important issue of this book. This book provides a critical review of the current state of science and will be useful for both scientists and students who are or would like to get involved in this area. Furthermore, this book addresses neuroscientists, physician and professionals from the industry, who would like to update themselves in this exciting and rapidly growing field of neuroscience.
650		0	_aNeurosciences.
650		0	_aNeurochemistry. _97117
650		0	_aMedicine _xResearch.
650		0	_aBiology _xResearch.
650		0	_aRegenerative medicine.
650	1	4	_aNeuroscience.
650	2	4	_aNeurochemistry. _97117
650	2	4	_aBiomedical Research.
650	2	4	_aRegenerative Medicine and Tissue Engineering.
700	1		_aUlrich, Henning. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aIlles, Peter. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aGlaser, Talita. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service)
856			_u#gotoholdings _yAccess resource
912			_aZDB-2-SBL
912			_aZDB-2-SXB
245			_h[E-Book]
999			_c103652 _d103652