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001 978-3-031-42648-3
003 DE-He213
005 20240729140253.0
007 cr nn 008mamaa
008 231011s2023 sz | s |||| 0|eng d
020 _a9783031426483
_9978-3-031-42648-3
024 7 _a10.1007/978-3-031-42648-3
_2doi
072 7 _aMMG
_2bicssc
072 7 _aMED071000
_2bisacsh
072 7 _aMKG
_2thema
245 1 0 _aSex and Gender Effects in Pharmacology
250 _a1st ed. 2023.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2023.
300 _aVIII, 288 p. 100 illus., 30 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aHandbook of Experimental Pharmacology,
_x1865-0325 ;
_v282
505 0 _aPart 1 Pharmacological Basic Principles -- The impact of sex and gender in medicine and pharmacology -- Sex differences in pharmacokinetics -- Clinical pharmacological considerations in transgender medicine -- Sex and gender differences in the pharmacology of the overactive urinary bladder -- Part 2 Pathologies of the Brain -- Sex differences in the evaluation and treatment of stroke -- Sex differences in pain and its treatment -- Therapeutics For Substance-Using Women: The Need To Elucidate Sex-Specific Targets For Better-Tailored Treatments -- Intersection of sex and depression: pathogenesis, presentation and treatments -- Biological and clinical implications of sex-specific differences in Alzheimer's disease -- Part 3 Diabetes, metabolic diseases & cardiovascular risk -- Gender Differences In Cardiovascular Health: Hormonal Effects on Cardiovscular Risk And Management. - Sex Differences in Glucose Homeostasis -- Sex-gender-based differences in metabolic diseases -- Hypothalamic pituitary gonadal axis disorders impacting fertility in both sexes and the potential of kisspeptin-based therapies to treat them.
520 _aBiological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the diagnosis and treatment of diseases affecting men and women, as well as of disease states that disproportionally affects women. Experts in various fields discuss both preclinical and clinical research that is contributing to a better understanding of the impact of sex in the presentation, etiology, treatment, and disease outcomes. Also discussed are the challenges encountered in implementing this growing body of knowledge into practice, as well as possible avenues to recognize and reduce health disparities between men and women so that therapeutic interventions are tailored and improved.
650 0 _aPharmacology.
_97400
650 0 _aImmunology.
650 0 _aNeurology .
650 0 _aEndocrinology.
_96049
650 0 _aCardiology.
650 1 4 _aPharmacology.
_97400
650 2 4 _aImmunology.
650 2 4 _aNeurology.
650 2 4 _aEndocrinology.
_96049
650 2 4 _aCardiology.
700 1 _aTsirka, Stella E.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aAcosta-Martinez, Maricedes.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
830 0 _aHandbook of Experimental Pharmacology,
_x1865-0325 ;
_v282
856 _u#gotoholdings
_yAccess resource
912 _aZDB-2-SBL
912 _aZDB-2-SXB
245 _h[E-Book]
999 _c103759
_d103759