000 04706cam a2200565Ia 4500
001 ocn811816466
003 OCoLC
005 20240729130855.0
006 m d
007 cr mn|||||||||
008 121004s2012 si o 000 0 eng d
040 _aHKP
_beng
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019 _a813396015
_a817819008
020 _a9789814343602
_q(electronic bk.)
020 _a9814343609
_q(electronic bk.)
020 _z9814343595
020 _z9789814343596
020 _a1283635933
020 _a9781283635936
020 _a661394839X
020 _a9786613948397
035 _a(OCoLC)811816466
_z(OCoLC)813396015
_z(OCoLC)817819008
072 7 _aMED
_x031000
_2bisacsh
072 7 _aMNG
_2bicssc
049 _aMAIN
245 0 0 _aFrom inflammation to cancer
_h[electronic resource] :
_badvances in diagnosis and therapy for gastrointestinal and hepatological diseases
_c
260 _aSingapore :
_bWorld Scientific,
_c2012.
300 _a1 online resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
520 _aInflammation and cancer are two major disorders that cause huge concerns in our society. However, what one may not know is that both diseases are closely associated and, in particular, both occur in the gastrointestinal tract and liver. This book describes the mechanics of how inflammation can progress to cancer in these organs. The authors in this book comprehensively discuss the different biomarkers for early diagnosis, and current therapeutic treatments for these diseases. All of these would allow us to better understand the pathogenesis of both diseases. As such, this book provides compreh.
505 0 _aSection I. Inflammation and cancer. ch. 1. General introduction / Chung Wah Wu and Jun Yu. ch. 2. General mechanisms of inflammation / Liwei Lu and Min Yang. ch. 3. Genetic and epigenetic alterations in inflammation-related cancers -- General mechanisms of cancers / Yasuyuki Okamoto and Yutaka Kondo. ch. 4. From inflammation to cancer: the molecular basis / Hongchuan Jin -- Section II. Models of chronic inflammation-induced cancers and their treatments. ch. 5. Advances in the treatment of Helicobacter pylori infection and gastric cancer / Guy D. Eslick. ch. 6. Inflammatory bowel disease and colorectal cancer and their treatment / Crispin Corte and Rupert WL Leong. ch. 7. Hepatitis B and hepatocellular carcinoma and their treatment / Chi-Jen Chu, Teh-Ia Huo and Shou-Dong Lee. ch. 8. Hepatitis C and hepatocellular carcinoma: implications for pathogenesis and treatment / Geoffrey C. Farrell. ch. 9. Advances in the interventional therapies for hepatocellular carcinoma / Carmen Chi Min Cho, Joyce Wai Yi Hui and Simon Chun Ho Yu -- Section III. Mediators in chronic inflammation and cancers. ch. 10. Exploration of cytokine signaling in clinical management of hepatocellular carcinoma / Xuelian Zhao and Xin Wei Wang. ch. 11. Role of nuclear factor-[symbol]B pathway in gastrointestinal inflammation and cancer / Muthu K. Shanmugam [and others]. ch. 12. Novel mediators for chronic inflammation and oncogenic transformation: Tumor Necrosis Factor (TNF)-[symbol] / Naofumi Mukaida and Boryana K. Popivanova. ch. 13. Peroxisome Proliferator Activated Receptor-[symbol] (PPAR[symbol]) : roles in chronic inflammation and intestinal oncogenic transformation / Ioannis A. Voutsadakis. ch. 14. Proteinase-activated receptors / Hongying Wang -- Section IV. Molecular markers of cancers and their clinical implications. ch. 15. Use of tumor markers in the detection and management of patients with colorectal cancer / Michael J. Duffy. ch. 16. Genetic biomarkers for the diagnosis and prognosis of hepatocellular carcinoma / John M. Luk [and others] -- Section V. Summary. ch. 17. Current therapy and future perspectives for inflammation-associated cancer / L. Zhang and C.H. Cho.
590 _aMaster record variable field(s) change: 072
650 0 _aGastrointestinal system
_xCancer
_xDiagnosis.
650 0 _aGastrointestinal system
_xCancer
_xTreatment.
650 0 _aLiver
_xCancer
_xDiagnosis.
650 0 _aLiver
_xCancer
_xTreatment.
700 1 _aCho, C.-H.
_q(Chi-Hin)
700 1 _aYu, Jun.
856 _u#gotoholdings
_yAccess resource
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