000			04847cam a2200589Mi 4500
001			ocn891382815
003			OCoLC
005			20240729131714.0
006			m d
007			cr cn|||||||||
008			140919t20142014nyua ob 001 0 eng d
040			_aE7B _beng _erda _epn _cE7B _dOCLCO _dN$T _dYDXCP _dOCLCF _dOCL _dEBLCP _dOCLCQ
019			_a899993093 _a916949301 _a923676729 _a928196057 _a963747115 _a967766861 _a992888659
020			_a9781633218697 _q(electronic bk.)
020			_a1633218694 _q(electronic bk.)
020			_z9781614704263
035			_a844858 _b(N$T)
035			_a(OCoLC)891382815 _z(OCoLC)899993093 _z(OCoLC)916949301 _z(OCoLC)923676729 _z(OCoLC)928196057 _z(OCoLC)963747115 _z(OCoLC)967766861 _z(OCoLC)992888659
072		7	_aHEA _x039000 _2bisacsh
072		7	_aMED _x014000 _2bisacsh
072		7	_aMED _x022000 _2bisacsh
072		7	_aMED _x112000 _2bisacsh
072		7	_aMED _x045000 _2bisacsh
049			_aMAIN
100	1		_aMokra, Daniela, _eauthor.
245	1	0	_aAcute lung injury : _bepidemiology, health effects and therapeutic treatment strategies _c _h[E-Book]
264		1	_aNew York, New York : _bNova Science Publishers, Inc., _c2014.
300			_a1 online resource (98 pages) : _billustrations.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aPulmonary and Respiratory Diseases and Disorders
504			_aIncludes bibliographical references and index.
588	0		_aPrint version record.
505	0		_aACUTE LUNG INJURY: EPIDEMIOLOGY, HEALTH EFFECTS AND THERAPEUTIC TREATMENT STRATEGIES; ACUTE LUNG INJURY: EPIDEMIOLOGY, HEALTH EFFECTS AND THERAPEUTIC TREATMENT STRATEGIES; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: TRALI Not a Two Hit, But a Multi-Causal Model; Center for Clinical Transfusion Research, Sanquin Research, Leiden; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands; Abstract; Introduction; Threshold Models; A More General Threshold Model of Multi-Causality; The Sufficient Cause Model; Discussion.
505	8		_aConclusionReferences; Chapter 2: Mechanisms and Prevention of Pulmonary Microvascular Hyperpermeability in Acute Lung Injury; Abstract; Introduction; Pulmonary Microvascular Hyperpermeability; in Acute Lung Injury; The Mechanisms of Pulmonary Microvascular Hyperpermeability in Acute Lung Injury; Macrophages; Neutrophils; Platelets; Cell Organelles; Small G Protein; Calcium; HMGB1; Cell Junctions; Nitric Oxide (NO) and Inducible Nitric Oxide Synthase (iNOS); Focal Adhesions (FAs) Complex and FA Kinase (FAK); Hyperoxia; Prospective Approach to Heal ALI; References.
505	8		_aChapter 3: Pharmacological Therapies for Acute Respiratory Distress SyndromeAbstract; Introduction; Corticosteroids; Neutrophil Elastase Inhibitors; Anticoagulant Therapies; Conclusion; References; Chapter 4: Novel Trends in Pharmacotherapy of Acute Lung Injury and Acute Respiratory Distress Syndrome; ABSTRACT; Definition of ALI/ARDS; Pathophysiology of ALI/ARDS as a Rationale for the Treatment; Pharmacotherapy of ALI/ARDS; Types, Dosage and Delivery of Exogenous Surfactants; Effects of Surfactant Administration; Complications of Surfactant Administration.
505	8		_aSurfactant Treatment in the Neonates and ChildrenSurfactant Treatment in the Adult Patients; Inhaled Nitric Oxide (iNO); Aerosolized Prostacyclin; Non-conventional Approaches (Cell and/or Gene Therapy); Cell-Based Approaches; Gene-Based Therapy; Cell-Delivered Gene Therapy; Conclusion; References; Editor Contact Information; Index.
520			_aIn this book, authors review the current knowledge on acute lung injury (ALI). ALI/acute respiratory distress syndrome (ARDS) is characterized by diffuse alveolar damage, alveolar capillary leakage, lung edema, neutrophil-derived inflammation, and surfactant dysfunction. These changes lead to clinical manifestations of decreased lung compliance, severe hypoxemia, and bilateral pulmonary infiltrates. In the first chapter the authors describe how two different models of multi-causality (intuitively appealing threshold model and abstract sufficient cause model), both of which are commonly used in.
590			_aMaster record variable field(s) change: 650
650		0	_aRespiratory distress syndrome, Adult _vCongresses.
650		0	_aRespiratory intensive care _vCongresses.
650		0	_aLungs _xWounds and injuries _vCongresses.
830		0	_aPulmonary and Respiratory Diseases and Disorders.
856			_u#gotoholdings _yAccess resource
938			_aEBL - Ebook Library _bEBLB _nEBL2119810
938			_aebrary _bEBRY _nebr10929389
938			_aEBSCOhost _bEBSC _n844858
938			_aYBP Library Services _bYANK _n12042595
942			_n0
994			_a92 _bN$T
999			_c91944 _d91944